1niq
From Proteopedia
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(New page: 200px<br /><applet load="1niq" size="450" color="white" frame="true" align="right" spinBox="true" caption="1niq" /> '''Solution Structure of the HOO-Bm bound BLMT,...) |
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| - | [[Image:1niq.jpg|left|200px]]<br /><applet load="1niq" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1niq" /> | ||
| - | '''Solution Structure of the HOO-Bm bound BLMT, Transposon Tn5-encoding Bleomycin-binding Protein'''<br /> | ||
| - | == | + | ==Solution Structure of the HOO-Bm bound BLMT, Transposon Tn5-encoding Bleomycin-binding Protein== |
| - | + | <StructureSection load='1niq' size='340' side='right'caption='[[1niq]]' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1niq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NIQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NIQ FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 1 model</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BLM:BLEOMYCIN+A2'>BLM</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1niq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1niq OCA], [https://pdbe.org/1niq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1niq RCSB], [https://www.ebi.ac.uk/pdbsum/1niq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1niq ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BLE_KLEPN BLE_KLEPN] Binding protein with a strong affinity to the bleomycin family of antibiotics. Binds to CL990; an antimitotic-antibiotic compound. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ni/1niq_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1niq ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Klebsiella pneumoniae]] | [[Category: Klebsiella pneumoniae]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Sugiyama | + | [[Category: Sugiyama M]] |
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Current revision
Solution Structure of the HOO-Bm bound BLMT, Transposon Tn5-encoding Bleomycin-binding Protein
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