2out

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{{Seed}}
 
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[[Image:2out.png|left|200px]]
 
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==Solution Structure of HI1506, a Novel Two Domain Protein from Haemophilus influenzae==
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The line below this paragraph, containing "STRUCTURE_2out", creates the "Structure Box" on the page.
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<StructureSection load='2out' size='340' side='right'caption='[[2out]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2out]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OUT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OUT FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2out FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2out OCA], [https://pdbe.org/2out PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2out RCSB], [https://www.ebi.ac.uk/pdbsum/2out PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2out ProSAT]</span></td></tr>
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{{STRUCTURE_2out| PDB=2out | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/VG35_HAEIN VG35_HAEIN]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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HI1506 is a 128-residue hypothetical protein of unknown function from Haemophilus influenzae. It was originally annotated as a shorter 85-residue protein, but a more detailed sequence analysis conducted in our laboratory revealed that the full-length protein has an additional 43 residues on the C terminus, corresponding with a region initially ascribed to HI1507. As part of a larger effort to understand the functions of hypothetical proteins from Gram-negative bacteria, and H. influenzae in particular, we report here the three-dimensional solution NMR structure for the corrected full-length HI1506 protein. The structure consists of two well-defined domains, an alpha/beta 50-residue N-domain and a 3-alpha 32-residue C-domain, separated by an unstructured 30-residue linker. Both domains have positively charged surface patches and weak structural homology with folds that are associated with RNA binding, suggesting a possible functional role in binding distal nucleic acid sites.
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===Solution Structure of HI1506, a Novel Two Domain Protein from Haemophilus influenzae===
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Solution structure of HI1506, a novel two-domain protein from Haemophilus influenzae.,Sari N, He Y, Doseeva V, Surabian K, Ramprakash J, Schwarz F, Herzberg O, Orban J Protein Sci. 2007 May;16(5):977-82. Epub 2007 Mar 30. PMID:17400915<ref>PMID:17400915</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_17400915}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 2out" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 17400915 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_17400915}}
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__TOC__
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</StructureSection>
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==About this Structure==
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2OUT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OUT OCA].
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==Reference==
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Solution structure of HI1506, a novel two-domain protein from Haemophilus influenzae., Sari N, He Y, Doseeva V, Surabian K, Ramprakash J, Schwarz F, Herzberg O, Orban J, Protein Sci. 2007 May;16(5):977-82. Epub 2007 Mar 30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17400915 17400915]
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[[Category: Haemophilus influenzae]]
[[Category: Haemophilus influenzae]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Doseeva, V.]]
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[[Category: Doseeva V]]
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[[Category: He, Y.]]
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[[Category: He Y]]
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[[Category: Herzberg, O.]]
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[[Category: Herzberg O]]
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[[Category: Orban, J.]]
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[[Category: Orban J]]
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[[Category: S2F, Structure 2.Function Project.]]
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[[Category: Sari N]]
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[[Category: Sari, N.]]
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[[Category: Schwarz F]]
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[[Category: Schwarz, F.]]
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[[Category: Surabian K]]
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[[Category: Surabian, K.]]
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[[Category: Haemophilus influenzae]]
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[[Category: Hypothetical protein]]
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[[Category: Nmr]]
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[[Category: S2f]]
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[[Category: Structural genomic]]
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[[Category: Structure 2 function project]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 19:02:11 2008''
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Current revision

Solution Structure of HI1506, a Novel Two Domain Protein from Haemophilus influenzae

PDB ID 2out

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