1uxd

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{{Seed}}
 
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[[Image:1uxd.png|left|200px]]
 
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==Fructose repressor DNA-binding domain, NMR, 34 structures==
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The line below this paragraph, containing "STRUCTURE_1uxd", creates the "Structure Box" on the page.
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<StructureSection load='1uxd' size='340' side='right'caption='[[1uxd]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1uxd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UXD FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uxd OCA], [https://pdbe.org/1uxd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uxd RCSB], [https://www.ebi.ac.uk/pdbsum/1uxd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uxd ProSAT]</span></td></tr>
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{{STRUCTURE_1uxd| PDB=1uxd | SCENE= }}
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</table>
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== Function ==
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===FRUCTOSE REPRESSOR DNA-BINDING DOMAIN, NMR, 34 STRUCTURES===
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[https://www.uniprot.org/uniprot/CRA_ECOLI CRA_ECOLI] Global transcriptional regulator, which plays an important role in the regulation of carbon metabolism. Activates transcription of genes encoding biosynthetic and oxidative enzymes (involved in Krebs cycle, glyoxylate shunt and gluconeogenesis, such as ppsA and fbp). Represses genes involved in sugar catabolism, such as fruB, pfkA, pykF and adhE. Binds asymmetrically to the two half-sites of its operator.<ref>PMID:16115199</ref> <ref>PMID:8195118</ref> <ref>PMID:8230205</ref> <ref>PMID:8550429</ref> <ref>PMID:8577250</ref> <ref>PMID:8858581</ref> <ref>PMID:9084760</ref> <ref>PMID:9371462</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_9237914}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 9237914 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ux/1uxd_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_9237914}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1uxd ConSurf].
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1UXD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UXD OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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Three-dimensional structure of the DNA-binding domain of the fructose repressor from Escherichia coli by 1H and 15N NMR., Penin F, Geourjon C, Montserret R, Bockmann A, Lesage A, Yang YS, Bonod-Bidaud C, Cortay JC, Negre D, Cozzone AJ, Deleage G, J Mol Biol. 1997 Jul 18;270(3):496-510. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9237914 9237914]
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__TOC__
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[[Category: Escherichia coli]]
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</StructureSection>
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[[Category: Single protein]]
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[[Category: Escherichia coli K-12]]
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[[Category: Bockmann, A.]]
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[[Category: Large Structures]]
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[[Category: Bonod-Bidaud, C.]]
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[[Category: Bockmann A]]
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[[Category: Cortay, J C.]]
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[[Category: Bonod-Bidaud C]]
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[[Category: Cozzone, A J.]]
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[[Category: Cortay JC]]
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[[Category: Deleage, G.]]
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[[Category: Cozzone AJ]]
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[[Category: Geourjon, C.]]
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[[Category: Deleage G]]
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[[Category: Lesage, A.]]
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[[Category: Geourjon C]]
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[[Category: Montserret, R.]]
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[[Category: Lesage A]]
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[[Category: Negre, D.]]
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[[Category: Montserret R]]
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[[Category: Penin, F.]]
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[[Category: Negre D]]
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[[Category: Yang, Y.]]
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[[Category: Penin F]]
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[[Category: Dna-binding protein]]
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[[Category: Yang Y]]
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[[Category: Fructose repressor]]
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[[Category: Laci family]]
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[[Category: Transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 19:17:17 2008''
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Current revision

Fructose repressor DNA-binding domain, NMR, 34 structures

PDB ID 1uxd

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