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1wxf

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{{Seed}}
 
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[[Image:1wxf.png|left|200px]]
 
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<!--
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==E.coli NAD Synthetase==
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The line below this paragraph, containing "STRUCTURE_1wxf", creates the "Structure Box" on the page.
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<StructureSection load='1wxf' size='340' side='right'caption='[[1wxf]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1wxf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WXF FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wxf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wxf OCA], [https://pdbe.org/1wxf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wxf RCSB], [https://www.ebi.ac.uk/pdbsum/1wxf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wxf ProSAT]</span></td></tr>
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{{STRUCTURE_1wxf| PDB=1wxf | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NADE_ECOLI NADE_ECOLI] Catalyzes a key step in NAD biosynthesis, transforming deamido-NAD into NAD by a two-step reaction.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wx/1wxf_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wxf ConSurf].
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<div style="clear:both"></div>
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===E.coli NAD Synthetase===
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==See Also==
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*[[NAD synthase|NAD synthase]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_15699042}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 15699042 is the PubMed ID number.
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-->
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{{ABSTRACT_PUBMED_15699042}}
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==About this Structure==
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1WXF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXF OCA].
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==Reference==
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Structures of Escherichia coli NAD synthetase with substrates and products reveal mechanistic rearrangements., Jauch R, Humm A, Huber R, Wahl MC, J Biol Chem. 2005 Apr 15;280(15):15131-40. Epub 2005 Feb 7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15699042 15699042]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Huber, R.]]
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[[Category: Huber R]]
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[[Category: Humm, A.]]
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[[Category: Humm A]]
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[[Category: Jauch, R.]]
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[[Category: Jauch R]]
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[[Category: Wahl, M C.]]
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[[Category: Wahl MC]]
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[[Category: E coli]]
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[[Category: Nad]]
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[[Category: Nade]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 19:45:30 2008''
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Current revision

E.coli NAD Synthetase

PDB ID 1wxf

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