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1u7p

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{{Seed}}
 
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[[Image:1u7p.png|left|200px]]
 
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<!--
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==X-ray Crystal Structure of the Hypothetical Phosphotyrosine Phosphatase MDP-1 of the Haloacid Dehalogenase Superfamily==
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The line below this paragraph, containing "STRUCTURE_1u7p", creates the "Structure Box" on the page.
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<StructureSection load='1u7p' size='340' side='right'caption='[[1u7p]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1u7p]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U7P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U7P FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene></td></tr>
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{{STRUCTURE_1u7p| PDB=1u7p | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u7p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u7p OCA], [https://pdbe.org/1u7p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u7p RCSB], [https://www.ebi.ac.uk/pdbsum/1u7p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u7p ProSAT]</span></td></tr>
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</table>
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===X-ray Crystal Structure of the Hypothetical Phosphotyrosine Phosphatase MDP-1 of the Haloacid Dehalogenase Superfamily===
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== Function ==
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[https://www.uniprot.org/uniprot/MGDP1_MOUSE MGDP1_MOUSE] Magnesium-dependent phosphatase which may act as a tyrosine phosphatase.<ref>PMID:10889041</ref> <ref>PMID:11601995</ref> <ref>PMID:15461449</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_15461449}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 15461449 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u7/1u7p_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_15461449}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1U7P is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U7P OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u7p ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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X-ray crystal structure of the hypothetical phosphotyrosine phosphatase MDP-1 of the haloacid dehalogenase superfamily., Peisach E, Selengut JD, Dunaway-Mariano D, Allen KN, Biochemistry. 2004 Oct 12;43(40):12770-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15461449 15461449]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Single protein]]
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[[Category: Allen KN]]
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[[Category: Allen, K N.]]
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[[Category: Dunaway-Mariano D]]
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[[Category: Dunaway-Mariano, D.]]
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[[Category: Peisach E]]
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[[Category: Peisach, E.]]
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[[Category: Selengut JD]]
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[[Category: Selengut, J D.]]
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[[Category: Aspartate nucleophile]]
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[[Category: Class iii]]
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[[Category: Enzyme evolution]]
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[[Category: Had superfamily]]
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[[Category: Phosphoryl transfer]]
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[[Category: Phosphotyrosine phosphatase]]
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[[Category: Structural enzymology]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 20:03:49 2008''
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Current revision

X-ray Crystal Structure of the Hypothetical Phosphotyrosine Phosphatase MDP-1 of the Haloacid Dehalogenase Superfamily

PDB ID 1u7p

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