1udz

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:16, 3 April 2024) (edit) (undo)
 
(14 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1udz.png|left|200px]]
 
-
<!--
+
==Isoleucyl-tRNA synthetase editing domain==
-
The line below this paragraph, containing "STRUCTURE_1udz", creates the "Structure Box" on the page.
+
<StructureSection load='1udz' size='340' side='right'caption='[[1udz]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1udz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UDZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UDZ FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1udz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1udz OCA], [https://pdbe.org/1udz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1udz RCSB], [https://www.ebi.ac.uk/pdbsum/1udz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1udz ProSAT], [https://www.topsan.org/Proteins/RSGI/1udz TOPSAN]</span></td></tr>
-
{{STRUCTURE_1udz| PDB=1udz | SCENE= }}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/SYI_THET8 SYI_THET8] Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity).[HAMAP-Rule:MF_02003]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ud/1udz_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1udz ConSurf].
 +
<div style="clear:both"></div>
-
===Isoleucyl-tRNA synthetase editing domain===
+
==See Also==
-
 
+
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_14672940}}, adds the Publication Abstract to the page
+
[[Category: Large Structures]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 14672940 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_14672940}}
+
-
 
+
-
==About this Structure==
+
-
1UDZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UDZ OCA].
+
-
 
+
-
==Reference==
+
-
Crystal structures of the CP1 domain from Thermus thermophilus isoleucyl-tRNA synthetase and its complex with L-valine., Fukunaga R, Fukai S, Ishitani R, Nureki O, Yokoyama S, J Biol Chem. 2004 Feb 27;279(9):8396-402. Epub 2003 Dec 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14672940 14672940]
+
-
[[Category: Isoleucine--tRNA ligase]]
+
-
[[Category: Single protein]]
+
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
-
[[Category: Fukai, S.]]
+
[[Category: Fukai S]]
-
[[Category: Fukunaga, R.]]
+
[[Category: Fukunaga R]]
-
[[Category: Ishitani, R.]]
+
[[Category: Ishitani R]]
-
[[Category: Nureki, O.]]
+
[[Category: Nureki O]]
-
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+
[[Category: Yokoyama S]]
-
[[Category: Yokoyama, S.]]
+
-
[[Category: Aminoacyl-trna synthetase]]
+
-
[[Category: Cp1]]
+
-
[[Category: Editing]]
+
-
[[Category: National project on protein structural and functional analyse]]
+
-
[[Category: Nppsfa]]
+
-
[[Category: Riken structural genomics/proteomics initiative]]
+
-
[[Category: Rsgi]]
+
-
[[Category: Structural genomic]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 20:24:16 2008''
+

Current revision

Isoleucyl-tRNA synthetase editing domain

PDB ID 1udz

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1udz"
Personal tools