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1r44

From Proteopedia

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{{Seed}}
 
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[[Image:1r44.png|left|200px]]
 
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<!--
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==Crystal Structure of VanX==
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The line below this paragraph, containing "STRUCTURE_1r44", creates the "Structure Box" on the page.
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<StructureSection load='1r44' size='340' side='right'caption='[[1r44]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1r44]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecium Enterococcus faecium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R44 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R44 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1r44| PDB=1r44 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r44 OCA], [https://pdbe.org/1r44 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r44 RCSB], [https://www.ebi.ac.uk/pdbsum/1r44 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r44 ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of VanX===
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== Function ==
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[https://www.uniprot.org/uniprot/VANX_ENTFC VANX_ENTFC] Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_9702193}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 9702193 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r4/1r44_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_9702193}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1R44 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecium Enterococcus faecium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R44 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r44 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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The structure of VanX reveals a novel amino-dipeptidase involved in mediating transposon-based vancomycin resistance., Bussiere DE, Pratt SD, Katz L, Severin JM, Holzman T, Park CH, Mol Cell. 1998 Jul;2(1):75-84. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9702193 9702193]
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</StructureSection>
[[Category: Enterococcus faecium]]
[[Category: Enterococcus faecium]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Holzman, T.]]
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[[Category: Holzman T]]
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[[Category: Katz, L.]]
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[[Category: Katz L]]
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[[Category: Park, C H.]]
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[[Category: Park CH]]
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[[Category: Pratt, S D.]]
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[[Category: Pratt SD]]
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[[Category: Severin, J M.]]
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[[Category: Severin JM]]
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[[Category: Dipeptidase]]
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[[Category: E faecium]]
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[[Category: Vanx]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 20:34:20 2008''
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Current revision

Crystal Structure of VanX

PDB ID 1r44

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