1yq5

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[[Image:1yq5.png|left|200px]]
 
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==PRD1 vertex protein P5==
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The line below this paragraph, containing "STRUCTURE_1yq5", creates the "Structure Box" on the page.
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<StructureSection load='1yq5' size='340' side='right'caption='[[1yq5]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1yq5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacteria_phage_PRD1 Enterobacteria phage PRD1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YQ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YQ5 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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{{STRUCTURE_1yq5| PDB=1yq5 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yq5 OCA], [https://pdbe.org/1yq5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yq5 RCSB], [https://www.ebi.ac.uk/pdbsum/1yq5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yq5 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/P5_BPPRD P5_BPPRD] In association with P31 and P2, forms the spike complexes located at the 5-fold vertices of the capsid. Essential for viral infectivity.<ref>PMID:10956048</ref>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Comparisons of bacteriophage PRD1 and adenovirus protein structures and virion architectures have been instrumental in unraveling an evolutionary relationship and have led to a proposal of a phylogeny-based virus classification. The structure of the PRD1 spike protein P5 provides further insight into the evolution of viral proteins. The crystallized P5 fragment comprises two structural domains: a globular knob and a fibrous shaft. The head folds into a ten-stranded jelly roll beta barrel, which is structurally related to the tumor necrosis factor (TNF) and the PRD1 coat protein domains. The shaft domain is a structural counterpart to the adenovirus spike shaft. The structural relationships between PRD1, TNF, and adenovirus proteins suggest that the vertex proteins may have originated from an ancestral TNF-like jelly roll coat protein via a combination of gene duplication and deletion.
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===PRD1 vertex protein P5===
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The structure of the bacteriophage PRD1 spike sheds light on the evolution of viral capsid architecture.,Merckel MC, Huiskonen JT, Bamford DH, Goldman A, Tuma R Mol Cell. 2005 Apr 15;18(2):161-70. PMID:15837420<ref>PMID:15837420</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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The line below this paragraph, {{ABSTRACT_PUBMED_15837420}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 1yq5" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 15837420 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_15837420}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Enterobacteria phage PRD1]]
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1YQ5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_prd1 Enterobacteria phage prd1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YQ5 OCA].
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[[Category: Large Structures]]
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[[Category: Bamford DH]]
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==Reference==
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[[Category: Goldman A]]
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The structure of the bacteriophage PRD1 spike sheds light on the evolution of viral capsid architecture., Merckel MC, Huiskonen JT, Bamford DH, Goldman A, Tuma R, Mol Cell. 2005 Apr 15;18(2):161-70. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15837420 15837420]
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[[Category: Huiskonen JT]]
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[[Category: Enterobacteria phage prd1]]
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[[Category: Merckel MC]]
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[[Category: Single protein]]
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[[Category: Tuma R]]
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[[Category: Bamford, D H.]]
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[[Category: Goldman, A.]]
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[[Category: Huiskonen, J T.]]
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[[Category: Merckel, M C.]]
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[[Category: Tuma, R.]]
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[[Category: Beta-jelly-roll]]
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[[Category: Beta-spiral]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 20:49:56 2008''
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Current revision

PRD1 vertex protein P5

PDB ID 1yq5

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