2rb2

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{{Seed}}
 
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[[Image:2rb2.png|left|200px]]
 
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==3-methylbenzylazide in complex with T4 lysozyme L99A==
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The line below this paragraph, containing "STRUCTURE_2rb2", creates the "Structure Box" on the page.
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<StructureSection load='2rb2' size='340' side='right'caption='[[2rb2]], [[Resolution|resolution]] 1.46&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2rb2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RB2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RB2 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.463&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=263:1-(AZIDOMETHYL)-3-METHYLBENZENE'>263</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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{{STRUCTURE_2rb2| PDB=2rb2 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rb2 OCA], [https://pdbe.org/2rb2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rb2 RCSB], [https://www.ebi.ac.uk/pdbsum/2rb2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rb2 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rb/2rb2_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rb2 ConSurf].
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<div style="clear:both"></div>
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===3-methylbenzylazide in complex with T4 lysozyme L99A===
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==See Also==
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*[[Lysozyme 3D structures|Lysozyme 3D structures]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_18280498}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 18280498 is the PubMed ID number.
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</StructureSection>
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[[Category: Escherichia virus T4]]
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{{ABSTRACT_PUBMED_18280498}}
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[[Category: Large Structures]]
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[[Category: Boyce SE]]
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==About this Structure==
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[[Category: Graves AP]]
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2RB2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RB2 OCA].
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[[Category: Shoichet BK]]
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==Reference==
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Rescoring docking hit lists for model cavity sites: predictions and experimental testing., Graves AP, Shivakumar DM, Boyce SE, Jacobson MP, Case DA, Shoichet BK, J Mol Biol. 2008 Mar 28;377(3):914-34. Epub 2008 Jan 30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18280498 18280498]
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[[Category: Enterobacteria phage t4]]
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[[Category: Lysozyme]]
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[[Category: Single protein]]
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[[Category: Boyce, S E.]]
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[[Category: Graves, A P.]]
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[[Category: Shoichet, B K.]]
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[[Category: Hydrolase]]
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[[Category: Protein cavity]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 21:11:26 2008''
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Current revision

3-methylbenzylazide in complex with T4 lysozyme L99A

PDB ID 2rb2

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