2r1j

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{{Seed}}
 
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[[Image:2r1j.png|left|200px]]
 
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==Crystal Structure of the P22 c2 Repressor protein in complex with the synthetic operator 9T==
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The line below this paragraph, containing "STRUCTURE_2r1j", creates the "Structure Box" on the page.
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<StructureSection load='2r1j' size='340' side='right'caption='[[2r1j]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2r1j]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_virus_P22 Salmonella virus P22]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R1J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R1J FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.53&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r1j OCA], [https://pdbe.org/2r1j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r1j RCSB], [https://www.ebi.ac.uk/pdbsum/2r1j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r1j ProSAT]</span></td></tr>
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{{STRUCTURE_2r1j| PDB=2r1j | SCENE= }}
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</table>
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== Function ==
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===Crystal Structure of the P22 c2 Repressor protein in complex with the synthetic operator 9T===
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[https://www.uniprot.org/uniprot/RPC2_BPP22 RPC2_BPP22] This protein allows the phage to reside inactively in the chromosome of its host bacterium. This lysogenic state is maintained by binding of regulatory protein C2 to the OR and OL operators, preventing transcription of proteins necessary for lytic development.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 18237194 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r1/2r1j_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_18237194}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r1j ConSurf].
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2R1J is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_p22 Enterobacteria phage p22]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R1J OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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P22 c2 repressor-operator complex: mechanisms of direct and indirect readout., Watkins D, Hsiao C, Woods KK, Koudelka GB, Williams LD, Biochemistry. 2008 Feb 26;47(8):2325-38. Epub 2008 Feb 1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18237194 18237194]
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[[Category: Large Structures]]
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[[Category: Enterobacteria phage p22]]
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[[Category: Salmonella virus P22]]
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[[Category: Single protein]]
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[[Category: Hsiao C]]
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[[Category: Hsiao, C.]]
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[[Category: Koudelka GB]]
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[[Category: Koudelka, G B.]]
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[[Category: Watkins D]]
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[[Category: Watkins, D.]]
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[[Category: Williams LD]]
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[[Category: Williams, L D.]]
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[[Category: Woods K]]
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[[Category: Woods, K.]]
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[[Category: Dna-binding]]
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[[Category: Helix-turn-helix]]
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[[Category: Protein-dna complex]]
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[[Category: Repressor]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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[[Category: Transcription/dna complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 21:29:19 2008''
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Current revision

Crystal Structure of the P22 c2 Repressor protein in complex with the synthetic operator 9T

PDB ID 2r1j

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