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Template:STRUCTURE 2iko
From Proteopedia
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| - | {{ | + | {{Structure |
| - | |PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|2iko, resolution 1.90Å (<scene name='initialview01'> | + | |PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[2iko]], [[Resolution|resolution]] 1.90Å (<scene name='initialview01'>default scene</scene>)}}} |
|LIGAND= <scene name='pdbligand=7IG:5-{4-[(3,5-DIFLUOROBENZYL)AMINO]PHENYL}-6-ETHYLPYRIMIDINE-2,4-DIAMINE'>7IG</scene> | |LIGAND= <scene name='pdbligand=7IG:5-{4-[(3,5-DIFLUOROBENZYL)AMINO]PHENYL}-6-ETHYLPYRIMIDINE-2,4-DIAMINE'>7IG</scene> | ||
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Renin Renin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.15 3.4.23.15] </span> | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Renin Renin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.15 3.4.23.15] </span> | ||
|GENE= REN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= REN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| - | + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iko FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iko OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iko RCSB], [http://www.ebi.ac.uk/pdbsum/2iko PDBsum]</span> | |
| - | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iko FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iko OCA], [http://www. | + | |
|FUNCTION={{GO|id=GO:0016787 | text = hydrolase activity}}{{GO|id=GO:0008233 | text = peptidase activity}}{{GO|id=GO:0004194 | text = pepsin A activity}}{{GO|id=GO:0004195 | text = renin activity}}{{GO|id=GO:0005102 | text = receptor binding}}{{GO|id=GO:0004190 | text = aspartic-type endopeptidase activity}} | |FUNCTION={{GO|id=GO:0016787 | text = hydrolase activity}}{{GO|id=GO:0008233 | text = peptidase activity}}{{GO|id=GO:0004194 | text = pepsin A activity}}{{GO|id=GO:0004195 | text = renin activity}}{{GO|id=GO:0005102 | text = receptor binding}}{{GO|id=GO:0004190 | text = aspartic-type endopeptidase activity}} | ||
|PROCESS={{GO|id=GO:0043408 | text = regulation of MAPKKK cascade}}{{GO|id=GO:0008217 | text = regulation of blood pressure}}{{GO|id=GO:0006508 | text = proteolysis}}{{GO|id=GO:0002003 | text = angiotensin maturation}} | |PROCESS={{GO|id=GO:0043408 | text = regulation of MAPKKK cascade}}{{GO|id=GO:0008217 | text = regulation of blood pressure}}{{GO|id=GO:0006508 | text = proteolysis}}{{GO|id=GO:0002003 | text = angiotensin maturation}} | ||
|COMPONENT={{GO|id=GO:0005615 | text = extracellular space}}{{GO|id=GO:0016020 | text = membrane}} | |COMPONENT={{GO|id=GO:0005615 | text = extracellular space}}{{GO|id=GO:0016020 | text = membrane}} | ||
|SARESOURCES=<span class='plainlinks'>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR009007 Ipr009007], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001461 Ipr001461], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR012848 Ipr012848], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001969 Ipr001969]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00026 PF00026]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P00797 P00797]</span> | |SARESOURCES=<span class='plainlinks'>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR009007 Ipr009007], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001461 Ipr001461], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR012848 Ipr012848], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001969 Ipr001969]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00026 PF00026]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P00797 P00797]</span> | ||
| - | | | + | |uPDB=2IKO|CONSURF={{!}}- |
| + | {{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]] | ||
| + | {{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" | ||
| + | {{!}} '''Toggle Conservation Colors:''' | ||
| + | {{!}} align="left" style="background-color:#acfaac;border-top:2px solid #dddddd; border-right:2px solid #dddddd" {{!}} | ||
| + | Rows = identical sequences: | ||
| + | <jmol> | ||
| + | <jmolButton> | ||
| + | <script></script> | ||
| + | <text>A [x]</text> | ||
| + | <name>jmb_2iko_A</name> | ||
| + | <title>toggle chain A</title> | ||
| + | <jsscript>ConsurfChainButton(elementClicked)</jsscript> | ||
| + | <appendtargetsuffixtoid>true</appendtargetsuffixtoid> | ||
| + | </jmolButton> | ||
| + | </jmol> | ||
| + | <jmol> | ||
| + | <jmolButton> | ||
| + | <script></script> | ||
| + | <text>D [x]</text> | ||
| + | <name>jmb_2iko_D</name> | ||
| + | <title>toggle chain D</title> | ||
| + | <jsscript>ConsurfChainButton(elementClicked)</jsscript> | ||
| + | <appendtargetsuffixtoid>true</appendtargetsuffixtoid> | ||
| + | </jmolButton> | ||
| + | </jmol> | ||
| + | |||
}} | }} | ||
Current revision
| |||||||||
| 2iko, resolution 1.90Å () | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Ligands: | |||||||||
| Gene: | REN (Homo sapiens) | ||||||||
| Activity: | Renin, with EC number 3.4.23.15 | ||||||||
| |||||||||
| |||||||||
| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
