1rng

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{{Seed}}
 
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[[Image:1rng.png|left|200px]]
 
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==SOLUTION STRUCTURE OF THE CUUG HAIRPIN: A NOVEL RNA TETRALOOP MOTIF==
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The line below this paragraph, containing "STRUCTURE_1rng", creates the "Structure Box" on the page.
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<StructureSection load='1rng' size='340' side='right'caption='[[1rng]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1rng]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RNG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RNG FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rng OCA], [https://pdbe.org/1rng PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rng RCSB], [https://www.ebi.ac.uk/pdbsum/1rng PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rng ProSAT]</span></td></tr>
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{{STRUCTURE_1rng| PDB=1rng | SCENE= }}
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The solution structure of a uniformly 13C/15N-labeled CUUG RNA hairpin loop has been determined by multidimensional heteronuclear magnetic resonance spectroscopy in combination with distance geometry and restrained molecular dynamics calculations. The structure of this CUUG tetraloop represents a novel RNA loop motif where the first and last loop nucleotides form a standard Watson-Crick C-G base pair and the second loop nucleotide interacts directly with the closing base pair of the stem by folding into the minor groove. This structure helps explain why the closing base pair is phylogenetically conserved and indicates a six-nucleotide G(CUNG)C motif for the CUUG RNA tetraloop. Implications for the function of this CUUG tetraloop in ribosomal RNA and in RNA tertiary interactions are discussed.
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===SOLUTION STRUCTURE OF THE CUUG HAIRPIN: A NOVEL RNA TETRALOOP MOTIF===
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Solution structure of the CUUG hairpin loop: a novel RNA tetraloop motif.,Jucker FM, Pardi A Biochemistry. 1995 Nov 7;34(44):14416-27. PMID:7578046<ref>PMID:7578046</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_7578046}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 1rng" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 7578046 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_7578046}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RNG OCA].
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[[Category: Jucker FM]]
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[[Category: Pardi A]]
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==Reference==
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Solution structure of the CUUG hairpin loop: a novel RNA tetraloop motif., Jucker FM, Pardi A, Biochemistry. 1995 Nov 7;34(44):14416-27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7578046 7578046]
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[[Category: Jucker, F M.]]
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[[Category: Pardi, A.]]
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[[Category: Nmr]]
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[[Category: Rna]]
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[[Category: Tetraloop]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 21:43:35 2008''
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Current revision

SOLUTION STRUCTURE OF THE CUUG HAIRPIN: A NOVEL RNA TETRALOOP MOTIF

PDB ID 1rng

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