1r62

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{{Seed}}
 
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[[Image:1r62.png|left|200px]]
 
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==Crystal structure of the C-terminal Domain of the Two-Component System Transmitter Protein NRII (NtrB)==
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The line below this paragraph, containing "STRUCTURE_1r62", creates the "Structure Box" on the page.
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<StructureSection load='1r62' size='340' side='right'caption='[[1r62]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1r62]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R62 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R62 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r62 OCA], [https://pdbe.org/1r62 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r62 RCSB], [https://www.ebi.ac.uk/pdbsum/1r62 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r62 ProSAT]</span></td></tr>
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{{STRUCTURE_1r62| PDB=1r62 | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of the C-terminal Domain of the Two-Component System Transmitter Protein NRII (NtrB)===
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[https://www.uniprot.org/uniprot/NTRB_ECOLI NTRB_ECOLI] NtrB acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of NtrC. In nitrogen limitation NtrB activates NtrC by phosphorylating it, while in nitrogen excess NtrC is dephosphorylated and consequently inactivated by NtrB.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 15157101 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r6/1r62_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_15157101}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r62 ConSurf].
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1R62 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R62 OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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Crystal structure of the C-terminal domain of the two-component system transmitter protein nitrogen regulator II (NRII; NtrB), regulator of nitrogen assimilation in Escherichia coli., Song Y, Peisach D, Pioszak AA, Xu Z, Ninfa AJ, Biochemistry. 2004 Jun 1;43(21):6670-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15157101 15157101]
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[[Category: Escherichia coli K-12]]
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[[Category: Escherichia coli]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Ninfa AJ]]
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[[Category: Ninfa, A J.]]
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[[Category: Peisach D]]
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[[Category: Peisach, D.]]
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[[Category: Pioszak AA]]
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[[Category: Pioszak, A A.]]
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[[Category: Song Y]]
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[[Category: Song, Y.]]
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[[Category: Xu Z]]
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[[Category: Xu, Z.]]
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[[Category: Histidine kinase]]
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[[Category: Nrii]]
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[[Category: Pii]]
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[[Category: Two component system]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 22:56:48 2008''
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Current revision

Crystal structure of the C-terminal Domain of the Two-Component System Transmitter Protein NRII (NtrB)

PDB ID 1r62

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