2qdl

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[[Image:2qdl.png|left|200px]]
 
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==Crystal structure of scaffolding protein TtCheW from Thermoanaerobacter tengcongensis==
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The line below this paragraph, containing "STRUCTURE_2qdl", creates the "Structure Box" on the page.
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<StructureSection load='2qdl' size='340' side='right'caption='[[2qdl]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2qdl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caldanaerobacter_subterraneus_subsp._tengcongensis_MB4 Caldanaerobacter subterraneus subsp. tengcongensis MB4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QDL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QDL FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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{{STRUCTURE_2qdl| PDB=2qdl | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qdl OCA], [https://pdbe.org/2qdl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qdl RCSB], [https://www.ebi.ac.uk/pdbsum/2qdl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qdl ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8RBV8_CALS4 Q8RBV8_CALS4]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qd/2qdl_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qdl ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The crystal structure of the scaffolding protein CheW from Thermoanaerobacter tengcongensis (TtCheW) is reported with a resolution at 2.2A using molecular replacement. Based on the crystal structure TmCheA P4-P5-TmCheW from Thermotoga maritime reported by others, we modeled the TmCheA P4-P5-TtCheW complex and predicted that TtCheW is involved in a hydrophobic interaction with CheA, similar to that for TmCheW. We also found that the conserved motif "NxxGxIxP" from CheW plays an important role in CheA binding. The coincidence of the reported mutation sites related to CheW-MCP binding, and the predicted protein interaction region within the TtCheW molecule, suggest that CheW-MCP binding sites lie in the groove-shaped area between TtCheW and the CheA P4 domain within the assembled model.
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===Crystal structure of scaffolding protein TtCheW from Thermoanaerobacter tengcongensis===
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Crystal structure of scaffolding protein CheW from thermoanaerobacter tengcongensis.,Yao W, Shi L, Liang DC Biochem Biophys Res Commun. 2007 Oct 5;361(4):1027-32. Epub 2007 Jul 31. PMID:17681283<ref>PMID:17681283</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_17681283}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 2qdl" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 17681283 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_17681283}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Caldanaerobacter subterraneus subsp. tengcongensis MB4]]
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2QDL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermoanaerobacter_tengcongensis Thermoanaerobacter tengcongensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QDL OCA].
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[[Category: Large Structures]]
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[[Category: Liang DC]]
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==Reference==
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[[Category: Shi L]]
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Crystal structure of scaffolding protein CheW from thermoanaerobacter tengcongensis., Yao W, Shi L, Liang DC, Biochem Biophys Res Commun. 2007 Oct 5;361(4):1027-32. Epub 2007 Jul 31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17681283 17681283]
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[[Category: Yao W]]
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[[Category: Single protein]]
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[[Category: Thermoanaerobacter tengcongensis]]
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[[Category: Liang, D C.]]
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[[Category: Shi, L.]]
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[[Category: Yao, W.]]
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[[Category: Beta-barrel]]
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[[Category: Signaling protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 23:03:00 2008''
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Current revision

Crystal structure of scaffolding protein TtCheW from Thermoanaerobacter tengcongensis

PDB ID 2qdl

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