2dpr

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:25, 3 April 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2dpr.png|left|200px]]
 
-
<!--
+
==The crystal structures of the calcium-bound con-G and con-T(K7Glu) dimeric peptides demonstrate a novel metal-dependent helix-forming motif==
-
The line below this paragraph, containing "STRUCTURE_2dpr", creates the "Structure Box" on the page.
+
<StructureSection load='2dpr' size='340' side='right'caption='[[2dpr]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2dpr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Conus_tulipa Conus tulipa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DPR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DPR FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CGU:GAMMA-CARBOXY-GLUTAMIC+ACID'>CGU</scene></td></tr>
-
{{STRUCTURE_2dpr| PDB=2dpr | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dpr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dpr OCA], [https://pdbe.org/2dpr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dpr RCSB], [https://www.ebi.ac.uk/pdbsum/2dpr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dpr ProSAT]</span></td></tr>
-
 
+
</table>
-
===The crystal structures of the calcium-bound con-G and con-T(K7Gla) dimeric peptides demonstrate a novel metal-dependent helix-forming motif===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/CKT_CONTU CKT_CONTU] Conantokins inhibit N-methyl-D-aspartate (NMDA) receptors. This toxin inhibits both NR2A and NR2B subunits of N-methyl-D-aspartate (NMDA) receptor-mediated calcium influx in central nervous system neurons. Induces sleep-like symptoms in young mice and hyperactivity in older mice.<ref>PMID:2165278</ref>
-
 
+
== References ==
-
<!--
+
<references/>
-
The line below this paragraph, {{ABSTRACT_PUBMED_17243678}}, adds the Publication Abstract to the page
+
__TOC__
-
(as it appears on PubMed at http://www.pubmed.gov), where 17243678 is the PubMed ID number.
+
</StructureSection>
-
-->
+
[[Category: Conus tulipa]]
-
{{ABSTRACT_PUBMED_17243678}}
+
[[Category: Large Structures]]
-
 
+
[[Category: Castellino FJ]]
-
==About this Structure==
+
[[Category: Cnudde SE]]
-
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DPR OCA].
+
[[Category: Dai Q]]
-
 
+
[[Category: Geiger JH]]
-
==Reference==
+
[[Category: Prorok M]]
-
The crystal structures of the calcium-bound con-G and con-T[K7gamma] dimeric peptides demonstrate a metal-dependent helix-forming motif., Cnudde SE, Prorok M, Dai Q, Castellino FJ, Geiger JH, J Am Chem Soc. 2007 Feb 14;129(6):1586-93. Epub 2007 Jan 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17243678 17243678]
+
-
[[Category: Castellino, F J.]]
+
-
[[Category: Cnudde, S E.]]
+
-
[[Category: Dai, Q.]]
+
-
[[Category: Geiger, J H.]]
+
-
[[Category: Prorok, M.]]
+
-
[[Category: Con-t]]
+
-
[[Category: Conantoxin]]
+
-
[[Category: Gla-containing]]
+
-
[[Category: Nmdar antagonist]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 23:21:40 2008''
+

Current revision

The crystal structures of the calcium-bound con-G and con-T(K7Glu) dimeric peptides demonstrate a novel metal-dependent helix-forming motif

PDB ID 2dpr

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2dpr"
Personal tools