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1nov

From Proteopedia

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{{Seed}}
 
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[[Image:1nov.png|left|200px]]
 
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==NODAMURA VIRUS==
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The line below this paragraph, containing "STRUCTURE_1nov", creates the "Structure Box" on the page.
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<StructureSection load='1nov' size='340' side='right'caption='[[1nov]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1nov]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Nodamura_virus Nodamura virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NOV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NOV FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nov FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nov OCA], [https://pdbe.org/1nov PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nov RCSB], [https://www.ebi.ac.uk/pdbsum/1nov PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nov ProSAT]</span></td></tr>
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{{STRUCTURE_1nov| PDB=1nov | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CAPSD_NODAM CAPSD_NODAM] Capsid protein alpha self-assembles to form an icosahedral procapsid with a T=3 symmetry, about 30 nm in diameter, and consisting of 60 capsid proteins trimers. The capsid encapsulates the two genomic RNAs. Capsid maturation occurs via autoproteolytic cleavage of capsid protein alpha generating capsid protein beta and the membrane-active peptide gamma (By similarity). Peptide gamma: membrane-permeabilizing peptide produced by virus maturation, thereby creating the infectious virion. After endocytosis into the host cell, peptide gamma is probably exposed in endosomes, where it permeabilizes the endosomal membrane, facilitating translocation of viral capsid or RNA into the cytoplasm (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/no/1nov_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nov ConSurf].
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<div style="clear:both"></div>
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===NODAMURA VIRUS===
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==See Also==
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*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_15299863}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 15299863 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15299863}}
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==About this Structure==
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1NOV is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Nodamura_virus Nodamura virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NOV OCA].
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==Reference==
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Resolution of space-group ambiguity and structure determination of nodamura virus to 3.3 A resolution from pseudo-R32 (monoclinic) crystals., Zlotnick A, Natarajan P, Munshi S, Johnson JE, Acta Crystallogr D Biol Crystallogr. 1997 Nov 1;53(Pt 6):738-46. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15299863 15299863]
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[[Category: Nodamura virus]]
[[Category: Nodamura virus]]
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[[Category: Protein complex]]
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[[Category: Johnson JE]]
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[[Category: Johnson, J E.]]
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[[Category: Natarajan P]]
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[[Category: Natarajan, P.]]
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[[Category: Coat protein]]
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[[Category: Icosahedral virus]]
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[[Category: Insect virus]]
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[[Category: Nodamura virus]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 23:39:29 2008''
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Current revision

NODAMURA VIRUS

PDB ID 1nov

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