1yib

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{{Seed}}
 
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[[Image:1yib.png|left|200px]]
 
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==Crystal Structure of the Human EB1 C-terminal Dimerization Domain==
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The line below this paragraph, containing "STRUCTURE_1yib", creates the "Structure Box" on the page.
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<StructureSection load='1yib' size='340' side='right'caption='[[1yib]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1yib]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YIB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YIB FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yib FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yib OCA], [https://pdbe.org/1yib PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yib RCSB], [https://www.ebi.ac.uk/pdbsum/1yib PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yib ProSAT]</span></td></tr>
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{{STRUCTURE_1yib| PDB=1yib | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MARE1_HUMAN MARE1_HUMAN] Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.<ref>PMID:12388762</ref> <ref>PMID:21646404</ref> <ref>PMID:16109370</ref> <ref>PMID:19632184</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yi/1yib_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yib ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of the Human EB1 C-terminal Dimerization Domain===
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==See Also==
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*[[End-binding protein|End-binding protein]]
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*[[Microtubule-associated protein 3D structures|Microtubule-associated protein 3D structures]]
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== References ==
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The line below this paragraph, {{ABSTRACT_PUBMED_15699215}}, adds the Publication Abstract to the page
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<references/>
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(as it appears on PubMed at http://www.pubmed.gov), where 15699215 is the PubMed ID number.
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__TOC__
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</StructureSection>
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{{ABSTRACT_PUBMED_15699215}}
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==About this Structure==
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1YIB is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YIB OCA].
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==Reference==
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Structural determinants for EB1-mediated recruitment of APC and spectraplakins to the microtubule plus end., Slep KC, Rogers SL, Elliott SL, Ohkura H, Kolodziej PA, Vale RD, J Cell Biol. 2005 Feb 14;168(4):587-98. Epub 2005 Feb 7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15699215 15699215]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Elliott, S L.]]
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[[Category: Elliott SL]]
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[[Category: Kolodziej, P A.]]
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[[Category: Kolodziej PA]]
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[[Category: Ohkura, H.]]
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[[Category: Ohkura H]]
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[[Category: Rogers, S L.]]
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[[Category: Rogers SL]]
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[[Category: Slep, K C.]]
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[[Category: Slep KC]]
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[[Category: Vale, R D.]]
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[[Category: Vale RD]]
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[[Category: Coiled coil]]
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[[Category: Four helix bundle]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 23:54:51 2008''
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Current revision

Crystal Structure of the Human EB1 C-terminal Dimerization Domain

PDB ID 1yib

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