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2etn

From Proteopedia

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{{Seed}}
 
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[[Image:2etn.png|left|200px]]
 
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==Crystal structure of Thermus aquaticus Gfh1==
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The line below this paragraph, containing "STRUCTURE_2etn", creates the "Structure Box" on the page.
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<StructureSection load='2etn' size='340' side='right'caption='[[2etn]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2etn]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ETN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ETN FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2etn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2etn OCA], [https://pdbe.org/2etn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2etn RCSB], [https://www.ebi.ac.uk/pdbsum/2etn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2etn ProSAT]</span></td></tr>
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{{STRUCTURE_2etn| PDB=2etn | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of Thermus aquaticus Gfh1===
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[https://www.uniprot.org/uniprot/GFH1_THEAQ GFH1_THEAQ] Inhibits all catalytic activities of RNA polymerase (RNAP) by partially occluding its substrate-binding site and preventing NTP binding.<ref>PMID:11606592</ref> <ref>PMID:16337964</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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<!--
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_16337964}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 16337964 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/et/2etn_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_16337964}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2etn ConSurf].
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2ETN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ETN OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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Crystal structure of Thermus aquaticus Gfh1, a Gre-factor paralog that inhibits rather than stimulates transcript cleavage., Lamour V, Hogan BP, Erie DA, Darst SA, J Mol Biol. 2006 Feb 10;356(1):179-88. Epub 2005 Nov 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16337964 16337964]
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__TOC__
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[[Category: Single protein]]
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Thermus aquaticus]]
[[Category: Thermus aquaticus]]
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[[Category: Darst, S A.]]
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[[Category: Darst SA]]
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[[Category: Erie, D A.]]
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[[Category: Erie DA]]
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[[Category: Hogan, B P.]]
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[[Category: Hogan BP]]
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[[Category: Lamour, V.]]
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[[Category: Lamour V]]
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[[Category: Anti gre-factor]]
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[[Category: Rna polymerase]]
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[[Category: Transcript cleavage]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 03:26:58 2008''
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Current revision

Crystal structure of Thermus aquaticus Gfh1

PDB ID 2etn

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