1oxj

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{{Seed}}
 
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[[Image:1oxj.png|left|200px]]
 
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==Crystal structure of the Smaug RNA binding domain==
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The line below this paragraph, containing "STRUCTURE_1oxj", creates the "Structure Box" on the page.
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<StructureSection load='1oxj' size='340' side='right'caption='[[1oxj]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1oxj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OXJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OXJ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oxj OCA], [https://pdbe.org/1oxj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oxj RCSB], [https://www.ebi.ac.uk/pdbsum/1oxj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oxj ProSAT]</span></td></tr>
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{{STRUCTURE_1oxj| PDB=1oxj | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of the Smaug RNA binding domain===
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[https://www.uniprot.org/uniprot/SMG_DROME SMG_DROME] Translation regulator that binds to the 3'-UTR of specific mRNAs such as nanos (nos) and prevent their translation. Prevents translation of unlocalized nos in the bulk cytoplasm via the recruitment of cup.<ref>PMID:10488336</ref> <ref>PMID:10606265</ref> <ref>PMID:8895661</ref> <ref>PMID:14685270</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_12820967}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 12820967 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ox/1oxj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_12820967}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1oxj ConSurf].
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1OXJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OXJ OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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RNA recognition via the SAM domain of Smaug., Green JB, Gardner CD, Wharton RP, Aggarwal AK, Mol Cell. 2003 Jun;11(6):1537-48. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12820967 12820967]
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__TOC__
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</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Aggarwal, A K.]]
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[[Category: Aggarwal AK]]
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[[Category: Gardner, C D.]]
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[[Category: Gardner CD]]
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[[Category: Green, J B.]]
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[[Category: Green JB]]
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[[Category: Wharton, R P.]]
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[[Category: Wharton RP]]
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[[Category: Phat domain]]
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[[Category: Rna-binding protein]]
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[[Category: Sam domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 03:34:52 2008''
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Current revision

Crystal structure of the Smaug RNA binding domain

PDB ID 1oxj

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OCA

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