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1nr4

From Proteopedia

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{{Seed}}
 
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[[Image:1nr4.png|left|200px]]
 
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==High resolution crystal structures of thymus and activation-regulated chemokine==
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The line below this paragraph, containing "STRUCTURE_1nr4", creates the "Structure Box" on the page.
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<StructureSection load='1nr4' size='340' side='right'caption='[[1nr4]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1nr4]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NR4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NR4 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.72&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1nr4| PDB=1nr4 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nr4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nr4 OCA], [https://pdbe.org/1nr4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nr4 RCSB], [https://www.ebi.ac.uk/pdbsum/1nr4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nr4 ProSAT]</span></td></tr>
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</table>
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===High resolution crystal structures of thymus and activation-regulated chemokine===
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== Function ==
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[https://www.uniprot.org/uniprot/CCL17_HUMAN CCL17_HUMAN] Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4.<ref>PMID:10540332</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_12832759}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 12832759 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nr/1nr4_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_12832759}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1NR4 is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NR4 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nr4 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Structures of thymus and activation-regulated chemokine (TARC)., Asojo OA, Boulegue C, Hoover DM, Lu W, Lubkowski J, Acta Crystallogr D Biol Crystallogr. 2003 Jul;59(Pt 7):1165-73. Epub 2003, Jun 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12832759 12832759]
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<references/>
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[[Category: Single protein]]
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__TOC__
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[[Category: Asojo, O A.]]
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</StructureSection>
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[[Category: Boulegue, C.]]
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[[Category: Homo sapiens]]
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[[Category: Hoover, D M.]]
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[[Category: Large Structures]]
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[[Category: Lu, W.]]
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[[Category: Asojo OA]]
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[[Category: Lubkowski, J.]]
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[[Category: Boulegue C]]
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[[Category: Cc-chemokine]]
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[[Category: Hoover DM]]
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[[Category: Chemokine]]
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[[Category: Lu W]]
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[[Category: Chemotaxis]]
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[[Category: Lubkowski J]]
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[[Category: Cytokine]]
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[[Category: Tarc]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 03:50:46 2008''
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Current revision

High resolution crystal structures of thymus and activation-regulated chemokine

PDB ID 1nr4

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