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1py9

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{{Seed}}
 
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[[Image:1py9.png|left|200px]]
 
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<!--
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==The crystal structure of an autoantigen in multiple sclerosis==
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The line below this paragraph, containing "STRUCTURE_1py9", creates the "Structure Box" on the page.
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<StructureSection load='1py9' size='340' side='right'caption='[[1py9]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1py9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PY9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PY9 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1py9| PDB=1py9 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1py9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1py9 OCA], [https://pdbe.org/1py9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1py9 RCSB], [https://www.ebi.ac.uk/pdbsum/1py9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1py9 ProSAT]</span></td></tr>
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</table>
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===The crystal structure of an autoantigen in multiple sclerosis===
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== Disease ==
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[https://www.uniprot.org/uniprot/MOG_MOUSE MOG_MOUSE] Note=Reduced concentrations of Mog are observed in jimpy and quacking dysmyelinating mutant mice.
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== Function ==
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<!--
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[https://www.uniprot.org/uniprot/MOG_MOUSE MOG_MOUSE] Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion.<ref>PMID:12960396</ref>
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The line below this paragraph, {{ABSTRACT_PUBMED_12960396}}, adds the Publication Abstract to the page
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== Evolutionary Conservation ==
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(as it appears on PubMed at http://www.pubmed.gov), where 12960396 is the PubMed ID number.
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[[Image:Consurf_key_small.gif|200px|right]]
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-->
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Check<jmol>
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{{ABSTRACT_PUBMED_12960396}}
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/py/1py9_consurf.spt"</scriptWhenChecked>
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==About this Structure==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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1PY9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PY9 OCA].
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==Reference==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1py9 ConSurf].
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The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis., Clements CS, Reid HH, Beddoe T, Tynan FE, Perugini MA, Johns TG, Bernard CC, Rossjohn J, Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):11059-64. Epub 2003 Sep 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12960396 12960396]
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Single protein]]
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[[Category: Beddoe T]]
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[[Category: Beddoe, T.]]
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[[Category: Bernard CC]]
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[[Category: Bernard, C C.]]
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[[Category: Clements CS]]
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[[Category: Clements, C S.]]
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[[Category: Johns TG]]
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[[Category: Johns, T G.]]
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[[Category: Perugini MA]]
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[[Category: Perugini, M A.]]
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[[Category: Reid HH]]
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[[Category: Reid, H H.]]
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[[Category: Rossjohn J]]
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[[Category: Rossjohn, J.]]
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[[Category: Tynan FE]]
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[[Category: Tynan, F E.]]
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[[Category: Anti-parallel dimer]]
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[[Category: Immunoglobulin]]
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[[Category: Multiple sclerosis]]
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[[Category: Myelin sheath]]
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[[Category: Receptor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 03:51:42 2008''
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Current revision

The crystal structure of an autoantigen in multiple sclerosis

PDB ID 1py9

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