2fxt

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{{Seed}}
 
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[[Image:2fxt.png|left|200px]]
 
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==Crystal Structure of Yeast Tim44==
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The line below this paragraph, containing "STRUCTURE_2fxt", creates the "Structure Box" on the page.
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<StructureSection load='2fxt' size='340' side='right'caption='[[2fxt]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2fxt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FXT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FXT FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fxt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fxt OCA], [https://pdbe.org/2fxt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fxt RCSB], [https://www.ebi.ac.uk/pdbsum/2fxt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fxt ProSAT]</span></td></tr>
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{{STRUCTURE_2fxt| PDB=2fxt | SCENE= }}
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</table>
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== Function ==
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===Crystal Structure of Yeast Tim44===
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[https://www.uniprot.org/uniprot/TIM44_YEAST TIM44_YEAST] Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 and its co-chaperone (MGE1) to drive protein translocation into the matrix using ATP as an energy source.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_16647716}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 16647716 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fx/2fxt_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_16647716}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fxt ConSurf].
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2FXT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FXT OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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Crystal structure of yeast mitochondrial peripheral membrane protein Tim44p C-terminal domain., Josyula R, Jin Z, Fu Z, Sha B, J Mol Biol. 2006 Jun 9;359(3):798-804. Epub 2006 Apr 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16647716 16647716]
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Single protein]]
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[[Category: Josyula R]]
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[[Category: Josyula, R.]]
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[[Category: Sha B]]
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[[Category: Sha, B.]]
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[[Category: Mitochondrial translocase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 03:59:50 2008''
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Current revision

Crystal Structure of Yeast Tim44

PDB ID 2fxt

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