1oaz

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{{Seed}}
 
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[[Image:1oaz.png|left|200px]]
 
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==IgE Fv SPE7 complexed with a recombinant thioredoxin==
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The line below this paragraph, containing "STRUCTURE_1oaz", creates the "Structure Box" on the page.
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<StructureSection load='1oaz' size='340' side='right'caption='[[1oaz]], [[Resolution|resolution]] 2.78&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1oaz]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OAZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OAZ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.78&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oaz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oaz OCA], [https://pdbe.org/1oaz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oaz RCSB], [https://www.ebi.ac.uk/pdbsum/1oaz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oaz ProSAT]</span></td></tr>
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{{STRUCTURE_1oaz| PDB=1oaz | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/THIO_ECOLI THIO_ECOLI] Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oa/1oaz_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1oaz ConSurf].
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<div style="clear:both"></div>
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===IGE FV SPE7 COMPLEXED WITH A RECOMBINANT THIOREDOXIN===
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==See Also==
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*[[Thioredoxin 3D structures|Thioredoxin 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12610298}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 12610298 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12610298}}
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==About this Structure==
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1OAZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Rattus_rattus Rattus rattus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OAZ OCA].
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==Reference==
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Antibody multispecificity mediated by conformational diversity., James LC, Roversi P, Tawfik DS, Science. 2003 Feb 28;299(5611):1362-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12610298 12610298]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Rattus rattus]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Mus musculus]]
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[[Category: James, L C.]]
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[[Category: James LC]]
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[[Category: Roversi, P.]]
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[[Category: Roversi P]]
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[[Category: Tawfik, D.]]
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[[Category: Tawfik D]]
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[[Category: Allergy]]
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[[Category: Antibody]]
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[[Category: Conformational diversity]]
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[[Category: Ige]]
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[[Category: Multispecficity,redox-active center,electron transport]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 04:33:57 2008''
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Current revision

IgE Fv SPE7 complexed with a recombinant thioredoxin

PDB ID 1oaz

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