1ry9

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{{Seed}}
 
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[[Image:1ry9.png|left|200px]]
 
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==Spa15, a Type III Secretion Chaperone from Shigella flexneri==
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The line below this paragraph, containing "STRUCTURE_1ry9", creates the "Structure Box" on the page.
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<StructureSection load='1ry9' size='340' side='right'caption='[[1ry9]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ry9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RY9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RY9 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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{{STRUCTURE_1ry9| PDB=1ry9 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ry9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ry9 OCA], [https://pdbe.org/1ry9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ry9 RCSB], [https://www.ebi.ac.uk/pdbsum/1ry9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ry9 ProSAT]</span></td></tr>
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</table>
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===Spa15, a Type III Secretion Chaperone from Shigella flexneri===
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== Function ==
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[https://www.uniprot.org/uniprot/SPAK_SHIFL SPAK_SHIFL] Required for surface presentation of invasion plasmid antigens. Chaperone specialized in the storage of effectors within the bacterial cytoplasm, maintaining them in a secretion-competent state, and allowing their immediate delivery to target cells upon contact of the bacterium with the host cells. Has been shown to chaperone IpaA, IpgB1, OspC3 and probably also OspB.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_15088068}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 15088068 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ry/1ry9_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_15088068}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1RY9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RY9 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ry9 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Structure of Spa15, a type III secretion chaperone from Shigella flexneri with broad specificity., van Eerde A, Hamiaux C, Perez J, Parsot C, Dijkstra BW, EMBO Rep. 2004 May;5(5):477-83. Epub 2004 Apr 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15088068 15088068]
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Shigella flexneri]]
[[Category: Shigella flexneri]]
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[[Category: Single protein]]
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[[Category: Dijkstra BW]]
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[[Category: Dijkstra, B W.]]
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[[Category: Hamiaux C]]
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[[Category: Eerde, A van.]]
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[[Category: Parsot C]]
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[[Category: Hamiaux, C.]]
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[[Category: Perez J]]
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[[Category: Parsot, C.]]
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[[Category: Van Eerde A]]
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[[Category: Perez, J.]]
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[[Category: Alpha/beta fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 05:03:34 2008''
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Current revision

Spa15, a Type III Secretion Chaperone from Shigella flexneri

PDB ID 1ry9

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