1pry

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{{Seed}}
 
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[[Image:1pry.png|left|200px]]
 
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==Structure Determination of Fibrillarin Homologue From Hyperthermophilic Archaeon Pyrococcus furiosus (Pfu-65527)==
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The line below this paragraph, containing "STRUCTURE_1pry", creates the "Structure Box" on the page.
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<StructureSection load='1pry' size='340' side='right'caption='[[1pry]], [[Resolution|resolution]] 1.97&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1pry]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PRY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PRY FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.97&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pry FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pry OCA], [https://pdbe.org/1pry PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pry RCSB], [https://www.ebi.ac.uk/pdbsum/1pry PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pry ProSAT], [https://www.topsan.org/Proteins/SECSG/1pry TOPSAN]</span></td></tr>
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{{STRUCTURE_1pry| PDB=1pry | SCENE= }}
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</table>
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== Function ==
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===Structure Determination of Fibrillarin Homologue From Hyperthermophilic Archaeon Pyrococcus furiosus (Pfu-65527)===
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[https://www.uniprot.org/uniprot/FLPA_PYRFU FLPA_PYRFU] Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA (By similarity).[HAMAP-Rule:MF_00351]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 14975761 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pr/1pry_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_14975761}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pry ConSurf].
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1PRY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PRY OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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Structure determination of fibrillarin from the hyperthermophilic archaeon Pyrococcus furiosus., Deng L, Starostina NG, Liu ZJ, Rose JP, Terns RM, Terns MP, Wang BC, Biochem Biophys Res Commun. 2004 Mar 12;315(3):726-32. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14975761 14975761]
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[[Category: Large Structures]]
[[Category: Pyrococcus furiosus]]
[[Category: Pyrococcus furiosus]]
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[[Category: Single protein]]
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[[Category: Deng L]]
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[[Category: Deng, L.]]
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[[Category: Liu Z-J]]
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[[Category: Liu, Z J.]]
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[[Category: Rose JP]]
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[[Category: Rose, J P.]]
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[[Category: Starostina NG]]
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[[Category: SECSG, Southeast Collaboratory for Structural Genomics.]]
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[[Category: Terns MP]]
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[[Category: Starostina, N G.]]
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[[Category: Terns RM]]
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[[Category: Terns, M P.]]
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[[Category: Wang B-C]]
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[[Category: Terns, R M.]]
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[[Category: Wang, B C.]]
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[[Category: Fibrillarin]]
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[[Category: Methylation]]
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[[Category: Pfu-65527]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Pyrococcus furiosus]]
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[[Category: Ribosomal rna processing]]
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[[Category: Secsg]]
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[[Category: Snornp]]
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[[Category: Southeast collaboratory for structural genomic]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 05:09:34 2008''
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Current revision

Structure Determination of Fibrillarin Homologue From Hyperthermophilic Archaeon Pyrococcus furiosus (Pfu-65527)

PDB ID 1pry

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