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1y96

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{{Seed}}
 
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[[Image:1y96.png|left|200px]]
 
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==crystal structure of the Gemin6/Gemin7 heterodimer from the human SMN complex==
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The line below this paragraph, containing "STRUCTURE_1y96", creates the "Structure Box" on the page.
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<StructureSection load='1y96' size='340' side='right'caption='[[1y96]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1y96]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y96 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y96 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.002&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y96 OCA], [https://pdbe.org/1y96 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y96 RCSB], [https://www.ebi.ac.uk/pdbsum/1y96 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y96 ProSAT]</span></td></tr>
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{{STRUCTURE_1y96| PDB=1y96 | SCENE= }}
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</table>
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== Function ==
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===crystal structure of the Gemin6/Gemin7 heterodimer from the human SMN complex===
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[https://www.uniprot.org/uniprot/GEMI6_HUMAN GEMI6_HUMAN] The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus.<ref>PMID:11748230</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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<!--
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_15939020}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 15939020 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/y9/1y96_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_15939020}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1y96 ConSurf].
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1Y96 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y96 OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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The Gemin6-Gemin7 heterodimer from the survival of motor neurons complex has an Sm protein-like structure., Ma Y, Dostie J, Dreyfuss G, Van Duyne GD, Structure. 2005 Jun;13(6):883-92. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15939020 15939020]
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein complex]]
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[[Category: Large Structures]]
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[[Category: Dostie, J.]]
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[[Category: Dostie J]]
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[[Category: Dreyfuss, G.]]
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[[Category: Dreyfuss G]]
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[[Category: Duyne, G D.Van.]]
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[[Category: Ma Y]]
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[[Category: Ma, Y.]]
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[[Category: Van Duyne GD]]
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[[Category: Protein complex]]
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[[Category: Sm fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 05:33:57 2008''
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Current revision

crystal structure of the Gemin6/Gemin7 heterodimer from the human SMN complex

PDB ID 1y96

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