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Template:STRUCTURE 1xwd

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Current revision

1xwd, resolution 2.92Å ()

Ligands:

, ,

Gene:

CGA (Homo sapiens), FSHB (Homo sapiens), FSHR (Homo sapiens)

Structural annotation:
Resources:	CATH : 1Xwda00, 1Xwdb00, 1Xwdd00, 1Xwde00 InterPro : Ipr000476, Ipr002400, Ipr006208, Ipr001545, Ipr000276, Ipr001611, Ipr002131, Ipr002272, Ipr000372 Pfam : PF00236, PF00007, PF01462, PF00560 UniProt : P01215, P01225, P23945

Functional annotation:
Cellular component:	extracellular region soluble fraction membrane plasma membrane integral to membrane
Biological process:	signal transduction cell-cell signaling spermatogenesis Sertoli cell proliferation female gamete generation ovarian follicle development female pregnancy gonad development G-protein coupled receptor protein signaling pathway female gonad development
Molecular function:	hormone activity follicle-stimulating hormone activity protein heterodimerization activity signal transducer activity protein binding follicle-stimulating hormone receptor activity G-protein coupled receptor activity protein-hormone receptor activity receptor activity rhodopsin-like receptor activity

Evolutionary conservation:

Toggle Conservation Colors:

Rows = identical sequences:

Further Information:

Caveats,

Explanation,
Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/Template:STRUCTURE_1xwd"

@@ Line 1: / Line 1: @@
-{{StructureD
+{{Structure
-|PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|1xwd, resolution 2.92&Aring; (<scene name='initialview01'>initial scene</scene>)}}}
+|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1xwd]], [[Resolution|resolution]] 2.92&Aring; (<scene name='initialview01'>default scene</scene>)}}}
-|LIGAND= <scene name='pdbligand=NAG:SUGAR+(N-ACETYL-D-GLUCOSAMINE)'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
+|LIGAND= <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
 |GENE= CGA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), FSHB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), FSHR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
-|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00236 Hormone_6], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam01462 LRRNT], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00069 GHB]</span>
+|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xwd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xwd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xwd RCSB], [http://www.ebi.ac.uk/pdbsum/1xwd PDBsum]</span>
-|NONSTDRES=<scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xwd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xwd OCA], [http://www.ebi.ac.uk/pdbsum/1xwd PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1xwd RCSB]</span>
 |FUNCTION={{GO|id=GO:0005179 | text = hormone activity}}{{GO|id=GO:0016913 | text = follicle-stimulating hormone activity}}{{GO|id=GO:0046982 | text = protein heterodimerization activity}}{{GO|id=GO:0004871 | text = signal transducer activity}}{{GO|id=GO:0005515 | text = protein binding}}{{GO|id=GO:0004963 | text = follicle-stimulating hormone receptor activity}}{{GO|id=GO:0004930 | text = G-protein coupled receptor activity}}{{GO|id=GO:0016500 | text = protein-hormone receptor activity}}{{GO|id=GO:0004872 | text = receptor activity}}{{GO|id=GO:0001584 | text = rhodopsin-like receptor activity}}
 |PROCESS={{GO|id=GO:0007165 | text = signal transduction}}{{GO|id=GO:0007267 | text = cell-cell signaling}}{{GO|id=GO:0007283 | text = spermatogenesis}}{{GO|id=GO:0060011 | text = Sertoli cell proliferation}}{{GO|id=GO:0007292 | text = female gamete generation}}{{GO|id=GO:0001541 | text = ovarian follicle development}}{{GO|id=GO:0007565 | text = female pregnancy}}{{GO|id=GO:0008406 | text = gonad development}}{{GO|id=GO:0007186 | text = G-protein coupled receptor protein signaling pathway}}{{GO|id=GO:0008585 | text = female gonad development}}
 |COMPONENT={{GO|id=GO:0005576 | text = extracellular region}}{{GO|id=GO:0005625 | text = soluble fraction}}{{GO|id=GO:0016020 | text = membrane}}{{GO|id=GO:0005886 | text = plasma membrane}}{{GO|id=GO:0016021 | text = integral to membrane}}
 |SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1xwdA00 1Xwda00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1xwdB00 1Xwdb00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1xwdD00 1Xwdd00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1xwdE00 1Xwde00]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000476 Ipr000476], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002400 Ipr002400], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR006208 Ipr006208], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001545 Ipr001545], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000276 Ipr000276], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001611 Ipr001611], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002131 Ipr002131], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002272 Ipr002272], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000372 Ipr000372]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00236 PF00236], [http://pfam.sanger.ac.uk/family?acc=PF00007 PF00007], [http://pfam.sanger.ac.uk/family?acc=PF01462 PF01462], [http://pfam.sanger.ac.uk/family?acc=PF00560 PF00560]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P01215 P01215], [http://ca.expasy.org/cgi-bin/niceprot.pl?P01225 P01225], [http://ca.expasy.org/cgi-bin/niceprot.pl?P23945 P23945]</span>
-|FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=CGA CGA], [http://www.genecards.org/cgi-bin/carddisp.pl?id=FSHB FSHB], [http://www.genecards.org/cgi-bin/carddisp.pl?id=FSHR FSHR]</span>
+|uPDB=1XWD|CONSURF={{!}}-
+{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
+{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
+{{!}} '''Toggle Conservation Colors:'''
+{{!}} align="left" style="background-color:#acfaac;border-top:2px solid #dddddd; border-right:2px solid #dddddd" {{!}}
+Rows = identical sequences:
+<jmol>
+<jmolButton>
+<script></script>
+<text>A [x]</text>
+<name>jmb_1xwd_A</name>
+<title>toggle chain A</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
+<jmol>
+<jmolButton>
+<script></script>
+<text>D [x]</text>
+<name>jmb_1xwd_D</name>
+<title>toggle chain D</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
+<jmol>
+<jmolButton>
+<script></script>
+<text>B [x]</text>
+<name>jmb_1xwd_B</name>
+<title>toggle chain B</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
+<jmol>
+<jmolButton>
+<script></script>
+<text>E [x]</text>
+<name>jmb_1xwd_E</name>
+<title>toggle chain E</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
+<jmol>
+<jmolButton>
+<script></script>
+<text>C [x]</text>
+<name>jmb_1xwd_C</name>
+<title>toggle chain C</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
+<jmol>
+<jmolButton>
+<script></script>
+<text>F [x]</text>
+<name>jmb_1xwd_F</name>
+<title>toggle chain F</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
 }}

Template:STRUCTURE 1xwd

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