We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

1qd5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:15, 14 February 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1qd5.png|left|200px]]
 
-
<!--
+
==OUTER MEMBRANE PHOSPHOLIPASE A FROM ESCHERICHIA COLI==
-
The line below this paragraph, containing "STRUCTURE_1qd5", creates the "Structure Box" on the page.
+
<StructureSection load='1qd5' size='340' side='right'caption='[[1qd5]], [[Resolution|resolution]] 2.17&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1qd5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QD5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QD5 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.17&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene></td></tr>
-
{{STRUCTURE_1qd5| PDB=1qd5 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qd5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qd5 OCA], [https://pdbe.org/1qd5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qd5 RCSB], [https://www.ebi.ac.uk/pdbsum/1qd5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qd5 ProSAT]</span></td></tr>
-
 
+
</table>
-
===OUTER MEMBRANE PHOSPHOLIPASE A FROM ESCHERICHIA COLI===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/PA1_ECOLI PA1_ECOLI] Has broad substrate specificity including hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Strong expression leads to outer membrane breakdown and cell death; is dormant in normal growing cells. Required for efficient secretion of bacteriocins.
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_10537112}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 10537112 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qd/1qd5_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_10537112}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
1QD5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QD5 OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qd5 ConSurf].
-
 
+
<div style="clear:both"></div>
-
==Reference==
+
__TOC__
-
Structural evidence for dimerization-regulated activation of an integral membrane phospholipase., Snijder HJ, Ubarretxena-Belandia I, Blaauw M, Kalk KH, Verheij HM, Egmond MR, Dekker N, Dijkstra BW, Nature. 1999 Oct 14;401(6754):717-21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10537112 10537112]
+
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Blaauw, M.]]
+
[[Category: Blaauw M]]
-
[[Category: Dekker, N.]]
+
[[Category: Dekker N]]
-
[[Category: Dijkstra, B W.]]
+
[[Category: Dijkstra BW]]
-
[[Category: Egmond, M R.]]
+
[[Category: Egmond MR]]
-
[[Category: Kalk, K H.]]
+
[[Category: Kalk KH]]
-
[[Category: Snijder, H J.]]
+
[[Category: Snijder HJ]]
-
[[Category: Ubarretxena-Belandia, I.]]
+
[[Category: Ubarretxena-Belandia I]]
-
[[Category: Verheij, H M.]]
+
[[Category: Verheij HM]]
-
[[Category: Anti-parallel beta barrel]]
+
-
[[Category: Membrane phospholipase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 05:43:02 2008''
+

Current revision

OUTER MEMBRANE PHOSPHOLIPASE A FROM ESCHERICHIA COLI

PDB ID 1qd5

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools