2r5k

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{{Seed}}
 
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[[Image:2r5k.png|left|200px]]
 
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==Pentamer Structure of Major Capsid protein L1 of Human Papilloma Virus type 11==
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The line below this paragraph, containing "STRUCTURE_2r5k", creates the "Structure Box" on the page.
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<StructureSection load='2r5k' size='340' side='right'caption='[[2r5k]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2r5k]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_papillomavirus_11 Human papillomavirus 11]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R5K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R5K FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r5k OCA], [https://pdbe.org/2r5k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r5k RCSB], [https://www.ebi.ac.uk/pdbsum/2r5k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r5k ProSAT]</span></td></tr>
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{{STRUCTURE_2r5k| PDB=2r5k | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/VL1_HPV11 VL1_HPV11] Forms an icosahedral capsid with a T=7 symmetry and about 55 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. The capsid encapsulates the genomic DNA, but does not bind DNA. Essential for the initial attachment to the host cell (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r5/2r5k_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r5k ConSurf].
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<div style="clear:both"></div>
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===Pentamer Structure of Major Capsid protein L1 of Human Papilloma Virus type 11===
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==See Also==
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*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_17804402}}, adds the Publication Abstract to the page
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[[Category: Human papillomavirus 11]]
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(as it appears on PubMed at http://www.pubmed.gov), where 17804402 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Bishop B]]
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{{ABSTRACT_PUBMED_17804402}}
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[[Category: Chen XS]]
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[[Category: Dasgupta J]]
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==About this Structure==
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2R5K is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_papillomavirus_type_11 Human papillomavirus type 11]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R5K OCA].
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==Reference==
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Crystal structures of four types of human papillomavirus L1 capsid proteins: understanding the specificity of neutralizing monoclonal antibodies., Bishop B, Dasgupta J, Klein M, Garcea RL, Christensen ND, Zhao R, Chen XS, J Biol Chem. 2007 Oct 26;282(43):31803-11. Epub 2007 Sep 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17804402 17804402]
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[[Category: Human papillomavirus type 11]]
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[[Category: Single protein]]
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[[Category: Bishop, B.]]
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[[Category: Chen, X S.]]
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[[Category: Dasgupta, J.]]
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[[Category: Capsid]]
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[[Category: Capsid protein]]
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[[Category: Hpv11]]
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[[Category: Late protein]]
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[[Category: Pentamer]]
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[[Category: Structure]]
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[[Category: Type specific epitope]]
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[[Category: Viral protein]]
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[[Category: Virion]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 06:18:05 2008''
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Current revision

Pentamer Structure of Major Capsid protein L1 of Human Papilloma Virus type 11

PDB ID 2r5k

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