1pip

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{{Seed}}
 
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[[Image:1pip.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF PAPAIN-SUCCINYL-GLN-VAL-VAL-ALA-ALA-P-NITROANILIDE COMPLEX AT 1.7 ANGSTROMS RESOLUTION: NONCOVALENT BINDING MODE OF A COMMON SEQUENCE OF ENDOGENOUS THIOL PROTEASE INHIBITORS==
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The line below this paragraph, containing "STRUCTURE_1pip", creates the "Structure Box" on the page.
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<StructureSection load='1pip' size='340' side='right'caption='[[1pip]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1pip]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Carica_papaya Carica papaya]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PIP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PIP FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NIT:4-NITROANILINE'>NIT</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
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{{STRUCTURE_1pip| PDB=1pip | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pip FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pip OCA], [https://pdbe.org/1pip PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pip RCSB], [https://www.ebi.ac.uk/pdbsum/1pip PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pip ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PAPA1_CARPA PAPA1_CARPA]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pi/1pip_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pip ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF PAPAIN-SUCCINYL-GLN-VAL-VAL-ALA-ALA-P-NITROANILIDE COMPLEX AT 1.7 ANGSTROMS RESOLUTION: NONCOVALENT BINDING MODE OF A COMMON SEQUENCE OF ENDOGENOUS THIOL PROTEASE INHIBITORS===
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==See Also==
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*[[Papain|Papain]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_1445868}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 1445868 is the PubMed ID number.
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{{ABSTRACT_PUBMED_1445868}}
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==About this Structure==
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1PIP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Carica_papaya Carica papaya]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PIP OCA].
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==Reference==
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Crystal structure of papain-succinyl-Gln-Val-Val-Ala-Ala-p-nitroanilide complex at 1.7-A resolution: noncovalent binding mode of a common sequence of endogenous thiol protease inhibitors., Yamamoto A, Tomoo K, Doi M, Ohishi H, Inoue M, Ishida T, Yamamoto D, Tsuboi S, Okamoto H, Okada Y, Biochemistry. 1992 Nov 24;31(46):11305-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1445868 1445868]
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[[Category: Carica papaya]]
[[Category: Carica papaya]]
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[[Category: Papain]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Doi M]]
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[[Category: Doi, M.]]
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[[Category: Inoue M]]
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[[Category: Inoue, M.]]
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[[Category: Ishida T]]
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[[Category: Ishida, T.]]
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[[Category: Ohishi H]]
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[[Category: Ohishi, H.]]
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[[Category: Okada Y]]
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[[Category: Okada, Y.]]
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[[Category: Okamoto H]]
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[[Category: Okamoto, H.]]
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[[Category: Tomoo K]]
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[[Category: Tomoo, K.]]
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[[Category: Tsuboi S]]
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[[Category: Tsuboi, S.]]
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[[Category: Yamamoto A]]
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[[Category: Yamamoto, A.]]
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[[Category: Yamamoto D]]
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[[Category: Yamamoto, D.]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 06:27:23 2008''
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Current revision

CRYSTAL STRUCTURE OF PAPAIN-SUCCINYL-GLN-VAL-VAL-ALA-ALA-P-NITROANILIDE COMPLEX AT 1.7 ANGSTROMS RESOLUTION: NONCOVALENT BINDING MODE OF A COMMON SEQUENCE OF ENDOGENOUS THIOL PROTEASE INHIBITORS

PDB ID 1pip

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