This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2ajh

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:41, 13 March 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2ajh.png|left|200px]]
 
-
<!--
+
==Crystal structure of the editing domain of E. coli leucyl-tRNA synthetase complexes with methionine==
-
The line below this paragraph, containing "STRUCTURE_2ajh", creates the "Structure Box" on the page.
+
<StructureSection load='2ajh' size='340' side='right'caption='[[2ajh]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2ajh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AJH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AJH FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MET:METHIONINE'>MET</scene></td></tr>
-
{{STRUCTURE_2ajh| PDB=2ajh | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ajh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ajh OCA], [https://pdbe.org/2ajh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ajh RCSB], [https://www.ebi.ac.uk/pdbsum/2ajh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ajh ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/SYL_ECOLI SYL_ECOLI]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aj/2ajh_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ajh ConSurf].
 +
<div style="clear:both"></div>
-
===Crystal structure of the editing domain of E. coli leucyl-tRNA synthetase complexes with methionine===
+
==See Also==
-
 
+
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_16277600}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 16277600 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_16277600}}
+
-
 
+
-
==About this Structure==
+
-
2AJH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AJH OCA].
+
-
 
+
-
==Reference==
+
-
Crystal structures of the editing domain of Escherichia coli leucyl-tRNA synthetase and its complexes with Met and Ile reveal a lock-and-key mechanism for amino acid discrimination., Liu Y, Liao J, Zhu B, Wang ED, Ding J, Biochem J. 2006 Mar 1;394(Pt 2):399-407. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16277600 16277600]
+
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
-
[[Category: Leucine--tRNA ligase]]
+
[[Category: Large Structures]]
-
[[Category: Single protein]]
+
[[Category: Ding J]]
-
[[Category: Ding, J.]]
+
[[Category: Liao J]]
-
[[Category: Liao, J.]]
+
[[Category: Liu Y]]
-
[[Category: Liu, Y.]]
+
[[Category: Wang ED]]
-
[[Category: Wang, E D.]]
+
[[Category: Zhu B]]
-
[[Category: Zhu, B.]]
+
-
[[Category: Editing domain]]
+
-
[[Category: Leucyl-trna synthetase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 06:57:18 2008''
+

Current revision

Crystal structure of the editing domain of E. coli leucyl-tRNA synthetase complexes with methionine

PDB ID 2ajh

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2ajh"
Personal tools