3b60

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{{Seed}}
 
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[[Image:3b60.png|left|200px]]
 
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==Crystal Structure of MsbA from Salmonella typhimurium with AMPPNP, higher resolution form==
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The line below this paragraph, containing "STRUCTURE_3b60", creates the "Structure Box" on the page.
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<StructureSection load='3b60' size='340' side='right'caption='[[3b60]], [[Resolution|resolution]] 3.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3b60]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B60 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B60 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>
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{{STRUCTURE_3b60| PDB=3b60 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b60 OCA], [https://pdbe.org/3b60 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b60 RCSB], [https://www.ebi.ac.uk/pdbsum/3b60 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b60 ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of MsbA from Salmonella typhimurium with AMPPNP, higher resolution form===
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== Function ==
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[https://www.uniprot.org/uniprot/MSBA_SALTY MSBA_SALTY] Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 18024585 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/3b60_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_18024585}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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3B60 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B60 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3b60 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Flexibility in the ABC transporter MsbA: Alternating access with a twist., Ward A, Reyes CL, Yu J, Roth CB, Chang G, Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):19005-10. Epub 2007 Nov 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18024585 18024585]
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</StructureSection>
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[[Category: Salmonella typhimurium]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
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[[Category: Chang, G.]]
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[[Category: Chang G]]
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[[Category: Reyes, C L.]]
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[[Category: Reyes CL]]
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[[Category: Roth, C B.]]
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[[Category: Roth CB]]
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[[Category: Ward, A.]]
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[[Category: Ward A]]
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[[Category: Yu, J.]]
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[[Category: Yu J]]
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[[Category: Abc transporter]]
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[[Category: Atp-binding]]
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[[Category: Hydrolase]]
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[[Category: Inner membrane]]
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[[Category: Lipid flippase]]
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[[Category: Lipid transport]]
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[[Category: Membrane]]
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[[Category: Membrane protein]]
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[[Category: Msba]]
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[[Category: Nucleotide-binding]]
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[[Category: Transmembrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 07:01:20 2008''
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Current revision

Crystal Structure of MsbA from Salmonella typhimurium with AMPPNP, higher resolution form

PDB ID 3b60

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