2fqy

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{{Seed}}
 
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[[Image:2fqy.png|left|200px]]
 
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==PnrA from Treponema pallidum complexed with adenosine.==
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The line below this paragraph, containing "STRUCTURE_2fqy", creates the "Structure Box" on the page.
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<StructureSection load='2fqy' size='340' side='right'caption='[[2fqy]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2fqy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Treponema_pallidum Treponema pallidum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FQY FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene></td></tr>
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{{STRUCTURE_2fqy| PDB=2fqy | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fqy OCA], [https://pdbe.org/2fqy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fqy RCSB], [https://www.ebi.ac.uk/pdbsum/2fqy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fqy ProSAT]</span></td></tr>
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</table>
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===PnrA from Treponema pallidum complexed with adenosine.===
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== Function ==
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[https://www.uniprot.org/uniprot/TMPC_TREPA TMPC_TREPA] Binds purine nucleosides and may play a role in purine nucleoside uptake. May be part of an ABC-type nucleoside uptake system. Has highest affinity for guanosine, followed by inosine and adenosine. Has very low affinity for cytidine and does not bind thymidine.<ref>PMID:16418175</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_16418175}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 16418175 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fq/2fqy_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_16418175}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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2FQY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Treponema_pallidum Treponema pallidum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQY OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fqy ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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The PnrA (Tp0319; TmpC) lipoprotein represents a new family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC)-like operon in Treponema pallidum., Deka RK, Brautigam CA, Yang XF, Blevins JS, Machius M, Tomchick DR, Norgard MV, J Biol Chem. 2006 Mar 24;281(12):8072-81. Epub 2006 Jan 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16418175 16418175]
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<references/>
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[[Category: Single protein]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Treponema pallidum]]
[[Category: Treponema pallidum]]
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[[Category: Brautigam, C A.]]
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[[Category: Brautigam CA]]
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[[Category: Deka, R K.]]
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[[Category: Deka RK]]
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[[Category: Machius, M.]]
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[[Category: Machius M]]
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[[Category: Norgard, M V.]]
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[[Category: Norgard MV]]
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[[Category: Tomchick, D R.]]
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[[Category: Tomchick DR]]
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[[Category: Abc receptor protein]]
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[[Category: Nucleoside binding protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 07:10:26 2008''
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Current revision

PnrA from Treponema pallidum complexed with adenosine.

PDB ID 2fqy

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