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2guf

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{{Seed}}
 
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[[Image:2guf.png|left|200px]]
 
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<!--
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==In meso crystal structure of the cobalamin transporter, BtuB==
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The line below this paragraph, containing "STRUCTURE_2guf", creates the "Structure Box" on the page.
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<StructureSection load='2guf' size='340' side='right'caption='[[2guf]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2guf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GUF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GUF FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MPG:[(Z)-OCTADEC-9-ENYL]+(2R)-2,3-BIS(OXIDANYL)PROPANOATE'>MPG</scene></td></tr>
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{{STRUCTURE_2guf| PDB=2guf | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2guf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2guf OCA], [https://pdbe.org/2guf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2guf RCSB], [https://www.ebi.ac.uk/pdbsum/2guf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2guf ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BTUB_ECOLI BTUB_ECOLI] Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB. Is also a receptor for bacteriophages BF23 and C1, and for A and E colicins.[HAMAP-Rule:MF_01531]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gu/2guf_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2guf ConSurf].
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<div style="clear:both"></div>
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===In meso crystal structure of the cobalamin transporter, BtuB===
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==See Also==
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*[[BtuB 3D structures|BtuB 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_17028020}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 17028020 is the PubMed ID number.
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{{ABSTRACT_PUBMED_17028020}}
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==About this Structure==
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2GUF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GUF OCA].
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==Reference==
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In meso structure of the cobalamin transporter, BtuB, at 1.95 A resolution., Cherezov V, Yamashita E, Liu W, Zhalnina M, Cramer WA, Caffrey M, J Mol Biol. 2006 Dec 8;364(4):716-34. Epub 2006 Sep 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17028020 17028020]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Caffrey, M.]]
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[[Category: Caffrey M]]
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[[Category: Cherezov, V.]]
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[[Category: Cherezov V]]
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[[Category: Cramer, W A.]]
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[[Category: Cramer WA]]
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[[Category: Yamashita, E.]]
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[[Category: Yamashita E]]
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[[Category: Beta barrel]]
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[[Category: Btub]]
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[[Category: Cobalamin]]
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[[Category: Colicin]]
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[[Category: Cubic mesophase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 07:51:43 2008''
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Current revision

In meso crystal structure of the cobalamin transporter, BtuB

PDB ID 2guf

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