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1wsd

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{{Seed}}
 
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[[Image:1wsd.png|left|200px]]
 
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<!--
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==Alkaline M-protease form I crystal structure==
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The line below this paragraph, containing "STRUCTURE_1wsd", creates the "Structure Box" on the page.
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<StructureSection load='1wsd' size='340' side='right'caption='[[1wsd]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1wsd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkalihalobacillus_clausii_KSM-K16 Alkalihalobacillus clausii KSM-K16]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WSD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WSD FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1wsd| PDB=1wsd | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wsd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wsd OCA], [https://pdbe.org/1wsd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wsd RCSB], [https://www.ebi.ac.uk/pdbsum/1wsd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wsd ProSAT]</span></td></tr>
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</table>
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===Alkaline M-protease form I crystal strcuture===
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== Function ==
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[https://www.uniprot.org/uniprot/PRTM_ALKCK PRTM_ALKCK] Alkaline serine protease that cleaves various substrates, including N-succinyl-Ala-Ala-Pro-Phe-pNA, N-succinyl-Ala-Ala-Pro-MetpNA, oxidized insulin B chain, casein, hemoglobin and scleroproteins, such as keratin, alpha-keratin and elastin.<ref>PMID:7632397</ref>
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_9278275}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 9278275 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ws/1wsd_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_9278275}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1WSD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_sp. Bacillus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WSD OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wsd ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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High-resolution crystal structure of M-protease: phylogeny aided analysis of the high-alkaline adaptation mechanism., Shirai T, Suzuki A, Yamane T, Ashida T, Kobayashi T, Hitomi J, Ito S, Protein Eng. 1997 Jun;10(6):627-34. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9278275 9278275]
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<references/>
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[[Category: Bacillus sp.]]
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__TOC__
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[[Category: Single protein]]
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</StructureSection>
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[[Category: Ashida, T.]]
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[[Category: Alkalihalobacillus clausii KSM-K16]]
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[[Category: Hitomi, J.]]
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[[Category: Large Structures]]
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[[Category: Ito, S.]]
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[[Category: Ashida T]]
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[[Category: Kobayashi, T.]]
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[[Category: Hitomi J]]
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[[Category: Shirai, T.]]
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[[Category: Ito S]]
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[[Category: Suzuki, A.]]
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[[Category: Kobayashi T]]
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[[Category: Yamane, T.]]
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[[Category: Shirai T]]
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[[Category: Detergent enzyme]]
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[[Category: Suzuki A]]
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[[Category: High-alkaline]]
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[[Category: Yamane T]]
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[[Category: Subtilisin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 08:01:06 2008''
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Current revision

Alkaline M-protease form I crystal structure

PDB ID 1wsd

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