1pd1

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{{Seed}}
 
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[[Image:1pd1.png|left|200px]]
 
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==Crystal structure of the COPII coat subunit, Sec24, complexed with a peptide containing the DxE cargo sorting signal of yeast Sys1 protein==
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The line below this paragraph, containing "STRUCTURE_1pd1", creates the "Structure Box" on the page.
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<StructureSection load='1pd1' size='340' side='right'caption='[[1pd1]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1pd1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PD1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PD1 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1pd1| PDB=1pd1 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pd1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pd1 OCA], [https://pdbe.org/1pd1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pd1 RCSB], [https://www.ebi.ac.uk/pdbsum/1pd1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pd1 ProSAT]</span></td></tr>
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</table>
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===Crystal structure of the COPII coat subunit, Sec24, complexed with a peptide containing the DxE cargo sorting signal of yeast Sys1 protein===
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== Function ==
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[https://www.uniprot.org/uniprot/SEC24_YEAST SEC24_YEAST] Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SEC24 specifically recruits cargo proteins like BET1 or SYS1 to the COPII vesicles. The SEC23/24 complex is also involved in internalisation of plasma membrane proteins like the maltose transporter.<ref>PMID:8548805</ref> <ref>PMID:9023343</ref> <ref>PMID:9428766</ref> <ref>PMID:10198022</ref> <ref>PMID:10753972</ref> <ref>PMID:10749860</ref> <ref>PMID:11086000</ref> <ref>PMID:10720463</ref> <ref>PMID:10712514</ref> <ref>PMID:12941277</ref> <ref>PMID:12655150</ref> <ref>PMID:14627716</ref> <ref>PMID:16269340</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_12941276}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 12941276 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pd/1pd1_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_12941276}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1PD1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PD1 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pd1 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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SNARE selectivity of the COPII coat., Mossessova E, Bickford LC, Goldberg J, Cell. 2003 Aug 22;114(4):483-95. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12941276 12941276]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Single protein]]
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[[Category: Bickford LC]]
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[[Category: Bickford, L C.]]
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[[Category: Goldberg J]]
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[[Category: Goldberg, J.]]
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[[Category: Mossessova E]]
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[[Category: Mossessova, E.]]
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[[Category: Transport protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 08:19:29 2008''
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Current revision

Crystal structure of the COPII coat subunit, Sec24, complexed with a peptide containing the DxE cargo sorting signal of yeast Sys1 protein

PDB ID 1pd1

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