1mvg

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{{Seed}}
 
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[[Image:1mvg.png|left|200px]]
 
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==NMR solution structure of chicken Liver basic Fatty Acid Binding Protein (Lb-FABP)==
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The line below this paragraph, containing "STRUCTURE_1mvg", creates the "Structure Box" on the page.
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<StructureSection load='1mvg' size='340' side='right'caption='[[1mvg]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1mvg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MVG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MVG FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mvg OCA], [https://pdbe.org/1mvg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mvg RCSB], [https://www.ebi.ac.uk/pdbsum/1mvg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mvg ProSAT]</span></td></tr>
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{{STRUCTURE_1mvg| PDB=1mvg | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FABPL_CHICK FABPL_CHICK] Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. Binds 2 molecules of cholate per subunit.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mv/1mvg_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mvg ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Chicken liver basic fatty acid binding protein (Lb-FABP) belongs to the basic-type fatty acid binding proteins, a novel group of proteins isolated from liver of different non mammalian species whose structure is not known. The structure of Lb-FABP has been solved by (1)H NMR. The overall fold of Lb-FABP, common to the other proteins of the family, consists of ten antiparallel beta-strands organised in two nearly ortogonal beta-sheets with two alpha helices closing the protein cavity where small hydrophobic ligands can be bound. The binding specificity of the protein is not known, however, based on the high sequence and structural similarity with an orthologous protein, ileal lipid binding protein, it is suggested that bile acids may be the putative ligands.
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===NMR solution structure of chicken Liver basic Fatty Acid Binding Protein (Lb-FABP)===
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Solution structure of chicken liver basic fatty acid binding protein.,Vasile F, Ragona L, Catalano M, Zetta L, Perduca M, Monaco H, Molinari H J Biomol NMR. 2003 Feb;25(2):157-60. PMID:12652125<ref>PMID:12652125</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 1mvg" style="background-color:#fffaf0;"></div>
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==See Also==
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The line below this paragraph, {{ABSTRACT_PUBMED_12652125}}, adds the Publication Abstract to the page
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*[[Fatty acid-binding protein 3D structures|Fatty acid-binding protein 3D structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12652125 is the PubMed ID number.
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== References ==
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-->
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<references/>
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{{ABSTRACT_PUBMED_12652125}}
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__TOC__
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</StructureSection>
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==About this Structure==
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1MVG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MVG OCA].
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==Reference==
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Solution structure of chicken liver basic fatty acid binding protein., Vasile F, Ragona L, Catalano M, Zetta L, Perduca M, Monaco H, Molinari H, J Biomol NMR. 2003 Feb;25(2):157-60. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12652125 12652125]
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[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Catalano, M.]]
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[[Category: Catalano M]]
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[[Category: Molinari, H.]]
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[[Category: Molinari H]]
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[[Category: Monaco, H.]]
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[[Category: Monaco H]]
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[[Category: Perduca, M.]]
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[[Category: Perduca M]]
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[[Category: Ragona, L.]]
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[[Category: Ragona L]]
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[[Category: Vasile, F.]]
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[[Category: Vasile F]]
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[[Category: Zetta, L.]]
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[[Category: Zetta L]]
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[[Category: Beta-barrel]]
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[[Category: Calycin]]
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[[Category: Fatty acid binding protein]]
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[[Category: Helix-turn-helix motif]]
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[[Category: Ten antiparallel beta strand]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 08:30:17 2008''
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Current revision

NMR solution structure of chicken Liver basic Fatty Acid Binding Protein (Lb-FABP)

PDB ID 1mvg

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