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1t8d

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{{Seed}}
 
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[[Image:1t8d.png|left|200px]]
 
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==Structure of the C-type lectin domain of CD23==
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The line below this paragraph, containing "STRUCTURE_1t8d", creates the "Structure Box" on the page.
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<StructureSection load='1t8d' size='340' side='right'caption='[[1t8d]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1t8d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T8D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T8D FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t8d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t8d OCA], [https://pdbe.org/1t8d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t8d RCSB], [https://www.ebi.ac.uk/pdbsum/1t8d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t8d ProSAT]</span></td></tr>
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{{STRUCTURE_1t8d| PDB=1t8d | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FCER2_HUMAN FCER2_HUMAN] Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t8/1t8d_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t8d ConSurf].
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<div style="clear:both"></div>
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===Structure of the C-type lectin domain of CD23===
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==See Also==
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*[[CD23|CD23]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_16172256}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 16172256 is the PubMed ID number.
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-->
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{{ABSTRACT_PUBMED_16172256}}
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==About this Structure==
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1T8D is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T8D OCA].
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==Reference==
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The structure of human CD23 and its interactions with IgE and CD21., Hibbert RG, Teriete P, Grundy GJ, Beavil RL, Reljic R, Holers VM, Hannan JP, Sutton BJ, Gould HJ, McDonnell JM, J Exp Med. 2005 Sep 19;202(6):751-60. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16172256 16172256]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Gould, H J.]]
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[[Category: Gould HJ]]
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[[Category: Grundy, G J.]]
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[[Category: Grundy GJ]]
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[[Category: Hibbert, R G.]]
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[[Category: Hibbert RG]]
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[[Category: McDonnell, J M.]]
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[[Category: McDonnell JM]]
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[[Category: Sutton, B J.]]
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[[Category: Sutton BJ]]
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[[Category: Teriete, P.]]
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[[Category: Teriete P]]
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[[Category: C-type lectin]]
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[[Category: Fc receptor]]
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[[Category: Fcerii]]
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[[Category: Ige]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 08:50:53 2008''
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Current revision

Structure of the C-type lectin domain of CD23

PDB ID 1t8d

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