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2hw4

From Proteopedia

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{{Seed}}
 
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[[Image:2hw4.png|left|200px]]
 
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<!--
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==Crystal structure of human phosphohistidine phosphatase==
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The line below this paragraph, containing "STRUCTURE_2hw4", creates the "Structure Box" on the page.
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<StructureSection load='2hw4' size='340' side='right'caption='[[2hw4]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2hw4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HW4 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
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{{STRUCTURE_2hw4| PDB=2hw4 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hw4 OCA], [https://pdbe.org/2hw4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hw4 RCSB], [https://www.ebi.ac.uk/pdbsum/2hw4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hw4 ProSAT]</span></td></tr>
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</table>
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===Crystal structure of human phosphohistidine phosphatase===
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== Function ==
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[https://www.uniprot.org/uniprot/PHP14_HUMAN PHP14_HUMAN] Exhibits phosphohistidine phosphatase activity.
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_16990267}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 16990267 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hw/2hw4_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_16990267}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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2HW4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HW4 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hw4 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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First structure of a eukaryotic phosphohistidine phosphatase., Busam RD, Thorsell AG, Flores A, Hammarstrom M, Persson C, Hallberg BM, J Biol Chem. 2006 Nov 10;281(45):33830-4. Epub 2006 Sep 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16990267 16990267]
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C.]]
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[[Category: Arrowsmith C]]
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[[Category: Berg, S Van Den.]]
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[[Category: Berglund H]]
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[[Category: Berglund, H.]]
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[[Category: Busam RD]]
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[[Category: Busam, R D.]]
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[[Category: Collins R]]
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[[Category: Collins, R.]]
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[[Category: Edwards A]]
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[[Category: Edwards, A.]]
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[[Category: Ehn M]]
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[[Category: Ehn, M.]]
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[[Category: Flodin S]]
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[[Category: Flodin, S.]]
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[[Category: Flores A]]
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[[Category: Flores, A.]]
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[[Category: Graslund S]]
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[[Category: Graslund, S.]]
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[[Category: Hallberg BM]]
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[[Category: Hallberg, B M.]]
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[[Category: Hammarstrom M]]
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[[Category: Hammarstrom, M.]]
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[[Category: Hogbom M]]
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[[Category: Hogbom, M.]]
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[[Category: Holmberg Schiavone L]]
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[[Category: Kotenyova, T.]]
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[[Category: Kotenyova T]]
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[[Category: Nilsson-Ehle, P.]]
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[[Category: Nilsson-Ehle P]]
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[[Category: Nordlund, P.]]
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[[Category: Nordlund P]]
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[[Category: Nyman, T.]]
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[[Category: Nyman T]]
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[[Category: Ogg, D.]]
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[[Category: Ogg D]]
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[[Category: Persson, C.]]
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[[Category: Persson C]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Stenmark P]]
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[[Category: Schiavone, L Holmberg.]]
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[[Category: Sundstrom M]]
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[[Category: Stenmark, P.]]
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[[Category: Thorsell AG]]
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[[Category: Sundstrom, M.]]
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[[Category: Uppenberg J]]
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[[Category: Thorsell, A G.]]
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[[Category: Van Den Berg S]]
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[[Category: Uppenberg, J.]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J.]]
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[[Category: Human]]
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[[Category: Phosphatase]]
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[[Category: Phosphohistidine]]
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[[Category: Phpt1]]
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[[Category: Sgc]]
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[[Category: Structural genomic]]
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[[Category: Structural genomics consortium]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 09:07:17 2008''
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Current revision

Crystal structure of human phosphohistidine phosphatase

PDB ID 2hw4

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