1ygj

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{{Seed}}
 
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[[Image:1ygj.png|left|200px]]
 
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==Crystal Structure of Pyridoxal Kinase in Complex with Roscovitine and Derivatives==
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The line below this paragraph, containing "STRUCTURE_1ygj", creates the "Structure Box" on the page.
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<StructureSection load='1ygj' size='340' side='right'caption='[[1ygj]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ygj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ovis_aries Ovis aries]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YGJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YGJ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RMC:(2R)-2-({6-[BENZYL(METHYL)AMINO]-9-ISOPROPYL-9H-PURIN-2-YL}AMINO)BUTAN-1-OL'>RMC</scene></td></tr>
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{{STRUCTURE_1ygj| PDB=1ygj | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ygj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ygj OCA], [https://pdbe.org/1ygj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ygj RCSB], [https://www.ebi.ac.uk/pdbsum/1ygj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ygj ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PDXK_SHEEP PDXK_SHEEP] Required for synthesis of pyridoxal-5-phosphate from vitamin B6.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yg/1ygj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ygj ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of Pyridoxal Kinase in Complex with Roscovitine and Derivatives===
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==See Also==
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*[[Pyridoxal kinase|Pyridoxal kinase]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_15985434}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 15985434 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15985434}}
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==About this Structure==
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1YGJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Ovis_aries Ovis aries]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YGJ OCA].
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==Reference==
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Crystal structure of pyridoxal kinase in complex with roscovitine and derivatives., Tang L, Li MH, Cao P, Wang F, Chang WR, Bach S, Reinhardt J, Ferandin Y, Galons H, Wan Y, Gray N, Meijer L, Jiang T, Liang DC, J Biol Chem. 2005 Sep 2;280(35):31220-9. Epub 2005 Jun 28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15985434 15985434]
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[[Category: Ovis aries]]
[[Category: Ovis aries]]
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[[Category: Pyridoxal kinase]]
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[[Category: Bach S]]
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[[Category: Single protein]]
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[[Category: Cao P]]
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[[Category: Bach, S.]]
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[[Category: Chang W-R]]
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[[Category: Cao, P.]]
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[[Category: Ferandin Y]]
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[[Category: Chang, W R.]]
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[[Category: Galons H]]
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[[Category: Ferandin, Y.]]
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[[Category: Gray N]]
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[[Category: Galons, H.]]
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[[Category: Jiang T]]
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[[Category: Gray, N.]]
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[[Category: Koken M]]
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[[Category: Jiang, T.]]
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[[Category: Li M-H]]
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[[Category: Koken, M.]]
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[[Category: Liang D-C]]
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[[Category: Li, M H.]]
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[[Category: Meijer L]]
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[[Category: Liang, D C.]]
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[[Category: Reinhardt J]]
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[[Category: Meijer, L.]]
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[[Category: Tang L]]
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[[Category: Reinhardt, J.]]
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[[Category: Wan Y]]
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[[Category: Tang, L.]]
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[[Category: Wang F]]
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[[Category: Wan, Y.]]
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[[Category: Wang, F.]]
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[[Category: Alpha-beta structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 09:16:55 2008''
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Current revision

Crystal Structure of Pyridoxal Kinase in Complex with Roscovitine and Derivatives

PDB ID 1ygj

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