1yz7

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{{Seed}}
 
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[[Image:1yz7.png|left|200px]]
 
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==Crystal structure of a C-terminal segment of the alpha subunit of aIF2 from Pyrococcus abyssi==
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The line below this paragraph, containing "STRUCTURE_1yz7", creates the "Structure Box" on the page.
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<StructureSection load='1yz7' size='340' side='right'caption='[[1yz7]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1yz7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_abyssi Pyrococcus abyssi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YZ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YZ7 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.26&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yz7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yz7 OCA], [https://pdbe.org/1yz7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yz7 RCSB], [https://www.ebi.ac.uk/pdbsum/1yz7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yz7 ProSAT]</span></td></tr>
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{{STRUCTURE_1yz7| PDB=1yz7 | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of a C-terminal segment of the alpha subunit of aIF2 from Pyrococcus abyssi===
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[https://www.uniprot.org/uniprot/IF2A_PYRAB IF2A_PYRAB] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_15952781}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 15952781 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yz/1yz7_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_15952781}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yz7 ConSurf].
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1YZ7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_abyssi Pyrococcus abyssi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YZ7 OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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Structure-function relationships of the intact aIF2alpha subunit from the archaeon Pyrococcus abyssi., Yatime L, Schmitt E, Blanquet S, Mechulam Y, Biochemistry. 2005 Jun 21;44(24):8749-56. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15952781 15952781]
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[[Category: Large Structures]]
[[Category: Pyrococcus abyssi]]
[[Category: Pyrococcus abyssi]]
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[[Category: Single protein]]
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[[Category: Blanquet S]]
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[[Category: Blanquet, S.]]
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[[Category: Mechulam Y]]
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[[Category: Mechulam, Y.]]
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[[Category: Schmitt E]]
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[[Category: Schmitt, E.]]
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[[Category: Yatime L]]
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[[Category: Yatime, L.]]
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[[Category: Alpha-beta domain]]
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[[Category: Helical domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 09:18:42 2008''
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Current revision

Crystal structure of a C-terminal segment of the alpha subunit of aIF2 from Pyrococcus abyssi

PDB ID 1yz7

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