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1r8c

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{{Seed}}
 
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[[Image:1r8c.png|left|200px]]
 
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==Crystal Structures of an Archaeal Class I CCA-Adding Enzyme and Its Nucleotide==
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The line below this paragraph, containing "STRUCTURE_1r8c", creates the "Structure Box" on the page.
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<StructureSection load='1r8c' size='340' side='right'caption='[[1r8c]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1r8c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R8C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R8C FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=UTP:URIDINE+5-TRIPHOSPHATE'>UTP</scene></td></tr>
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{{STRUCTURE_1r8c| PDB=1r8c | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r8c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r8c OCA], [https://pdbe.org/1r8c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r8c RCSB], [https://www.ebi.ac.uk/pdbsum/1r8c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r8c ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CCA_ARCFU CCA_ARCFU] Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.<ref>PMID:14592988</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r8/1r8c_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r8c ConSurf].
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<div style="clear:both"></div>
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===Crystal Structures of an Archaeal Class I CCA-Adding Enzyme and Its Nucleotide===
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==See Also==
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*[[CCA-adding enzyme 3D structures|CCA-adding enzyme 3D structures]]
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== References ==
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 14636575 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_14636575}}
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==About this Structure==
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1R8C is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R8C OCA].
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==Reference==
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Crystal structures of an archaeal class I CCA-adding enzyme and its nucleotide complexes., Xiong Y, Li F, Wang J, Weiner AM, Steitz TA, Mol Cell. 2003 Nov;12(5):1165-72. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14636575 14636575]
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[[Category: Archaeoglobus fulgidus]]
[[Category: Archaeoglobus fulgidus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: TRNA adenylyltransferase]]
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[[Category: Li F]]
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[[Category: Li, F.]]
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[[Category: Steitz TA]]
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[[Category: Steitz, T A.]]
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[[Category: Wang J]]
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[[Category: Wang, J.]]
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[[Category: Weiner AM]]
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[[Category: Weiner, A M.]]
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[[Category: Xiong Y]]
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[[Category: Xiong, Y.]]
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[[Category: Cca adding enzyme]]
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[[Category: Incoming nucleotide]]
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[[Category: Nucleotidyltransferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 09:49:53 2008''
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Current revision

Crystal Structures of an Archaeal Class I CCA-Adding Enzyme and Its Nucleotide

PDB ID 1r8c

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