2bn0

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:46, 13 December 2023) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2bn0.png|left|200px]]
 
-
<!--
+
==Banana Lectin bound to Laminaribiose==
-
The line below this paragraph, containing "STRUCTURE_2bn0", creates the "Structure Box" on the page.
+
<StructureSection load='2bn0' size='340' side='right'caption='[[2bn0]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2bn0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Musa_acuminata Musa acuminata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BN0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BN0 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=PRD_900024:beta-laminaribiose'>PRD_900024</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
{{STRUCTURE_2bn0| PDB=2bn0 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bn0 OCA], [https://pdbe.org/2bn0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bn0 RCSB], [https://www.ebi.ac.uk/pdbsum/2bn0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bn0 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/O22321_MUSAC O22321_MUSAC]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bn/2bn0_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bn0 ConSurf].
 +
<div style="clear:both"></div>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
Banana lectin (Banlec) is a dimeric plant lectin from the jacalin-related lectin family. Banlec belongs to a subgroup of this family that binds to glucose/mannose, but is unique in recognizing internal alpha1,3 linkages as well as beta1,3 linkages at the reducing termini. Here we present the crystal structures of Banlec alone and with laminaribiose (LAM) (Glcbeta1, 3Glc) and Xyl-beta1,3-Man-alpha-O-Methyl. The structure of Banlec has a beta-prism-I fold, similar to other family members, but differs from them in its mode of sugar binding. The reducing unit of the sugar is inserted into the binding site causing the second saccharide unit to be placed in the opposite orientation compared with the other ligand-bound structures of family members. More importantly, our structures reveal the presence of a second sugar binding site that has not been previously reported in the literature. The residues involved in the second site are common to other lectins in this family, potentially signaling a new group of mannose-specific jacalin-related lectins (mJRL) with two sugar binding sites.
-
===BANANA LECTIN BOUND TO LAMINARIBIOSE===
+
Crystal structure of banana lectin reveals a novel second sugar binding site.,Meagher JL, Winter HC, Ezell P, Goldstein IJ, Stuckey JA Glycobiology. 2005 Oct;15(10):1033-42. Epub 2005 Jun 8. PMID:15944373<ref>PMID:15944373</ref>
-
 
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
<!--
+
</div>
-
The line below this paragraph, {{ABSTRACT_PUBMED_15944373}}, adds the Publication Abstract to the page
+
<div class="pdbe-citations 2bn0" style="background-color:#fffaf0;"></div>
-
(as it appears on PubMed at http://www.pubmed.gov), where 15944373 is the PubMed ID number.
+
== References ==
-
-->
+
<references/>
-
{{ABSTRACT_PUBMED_15944373}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
[[Category: Large Structures]]
-
2BN0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Musa_acuminata Musa acuminata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BN0 OCA].
+
-
 
+
-
==Reference==
+
-
Crystal structure of banana lectin reveals a novel second sugar binding site., Meagher JL, Winter HC, Ezell P, Goldstein IJ, Stuckey JA, Glycobiology. 2005 Oct;15(10):1033-42. Epub 2005 Jun 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15944373 15944373]
+
[[Category: Musa acuminata]]
[[Category: Musa acuminata]]
-
[[Category: Single protein]]
+
[[Category: Ezell P]]
-
[[Category: Ezell, P.]]
+
[[Category: Goldstein IJ]]
-
[[Category: Goldstein, I J.]]
+
[[Category: Meagher JL]]
-
[[Category: Meagher, J L.]]
+
[[Category: Stuckey JA]]
-
[[Category: Stuckey, J A.]]
+
[[Category: Winter HC]]
-
[[Category: Winter, H C.]]
+
-
[[Category: Banana lectin]]
+
-
[[Category: Lectin]]
+
-
[[Category: Mannose-specific jacalin-related lectin]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 09:54:59 2008''
+

Current revision

Banana Lectin bound to Laminaribiose

PDB ID 2bn0

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2bn0"
Personal tools