This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2et6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:19, 14 February 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2et6.png|left|200px]]
 
-
<!--
+
==(3R)-Hydroxyacyl-CoA Dehydrogenase Domain of Candida tropicalis Peroxisomal Multifunctional Enzyme Type 2==
-
The line below this paragraph, containing "STRUCTURE_2et6", creates the "Structure Box" on the page.
+
<StructureSection load='2et6' size='340' side='right'caption='[[2et6]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2et6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_tropicalis Candida tropicalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ET6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ET6 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.22&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2et6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2et6 OCA], [https://pdbe.org/2et6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2et6 RCSB], [https://www.ebi.ac.uk/pdbsum/2et6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2et6 ProSAT]</span></td></tr>
-
{{STRUCTURE_2et6| PDB=2et6 | SCENE= }}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/FOX2_CANTR FOX2_CANTR] Second trifunctional enzyme acting on the beta-oxidation pathway for fatty acids, possessing hydratase-dehydrogenase-epimerase activities. Converts trans-2-enoyl-CoA via D-3-hydroxyacyl-CoA to 3-ketoacyl-CoA.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/et/2et6_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2et6 ConSurf].
 +
<div style="clear:both"></div>
-
===(3R)-Hydroxyacyl-CoA Dehydrogenase Domain of Candida tropicalis Peroxisomal Multifunctional Enzyme Type 2===
+
==See Also==
-
 
+
*[[Alcohol dehydrogenase 3D structures|Alcohol dehydrogenase 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_16574148}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 16574148 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_16574148}}
+
-
 
+
-
==About this Structure==
+
-
2ET6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Candida_tropicalis Candida tropicalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ET6 OCA].
+
-
 
+
-
==Reference==
+
-
Crystal structure of yeast peroxisomal multifunctional enzyme: structural basis for substrate specificity of (3R)-hydroxyacyl-CoA dehydrogenase units., Ylianttila MS, Pursiainen NV, Haapalainen AM, Juffer AH, Poirier Y, Hiltunen JK, Glumoff T, J Mol Biol. 2006 May 19;358(5):1286-95. Epub 2006 Mar 30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16574148 16574148]
+
[[Category: Candida tropicalis]]
[[Category: Candida tropicalis]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Glumoff, T.]]
+
[[Category: Glumoff T]]
-
[[Category: Hiltunen, J K.]]
+
[[Category: Hiltunen JK]]
-
[[Category: Ylianttila, M S.]]
+
[[Category: Ylianttila MS]]
-
[[Category: Beta-oxidation]]
+
-
[[Category: Dehydrogenase]]
+
-
[[Category: Mfe-2]]
+
-
[[Category: Oxidoreductase]]
+
-
[[Category: Peroxisome]]
+
-
[[Category: Sdr]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 10:13:06 2008''
+

Current revision

(3R)-Hydroxyacyl-CoA Dehydrogenase Domain of Candida tropicalis Peroxisomal Multifunctional Enzyme Type 2

PDB ID 2et6

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools