2et6

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{{Seed}}
 
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[[Image:2et6.png|left|200px]]
 
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==(3R)-Hydroxyacyl-CoA Dehydrogenase Domain of Candida tropicalis Peroxisomal Multifunctional Enzyme Type 2==
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The line below this paragraph, containing "STRUCTURE_2et6", creates the "Structure Box" on the page.
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<StructureSection load='2et6' size='340' side='right'caption='[[2et6]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2et6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_tropicalis Candida tropicalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ET6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ET6 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.22&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2et6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2et6 OCA], [https://pdbe.org/2et6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2et6 RCSB], [https://www.ebi.ac.uk/pdbsum/2et6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2et6 ProSAT]</span></td></tr>
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{{STRUCTURE_2et6| PDB=2et6 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FOX2_CANTR FOX2_CANTR] Second trifunctional enzyme acting on the beta-oxidation pathway for fatty acids, possessing hydratase-dehydrogenase-epimerase activities. Converts trans-2-enoyl-CoA via D-3-hydroxyacyl-CoA to 3-ketoacyl-CoA.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/et/2et6_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2et6 ConSurf].
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<div style="clear:both"></div>
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===(3R)-Hydroxyacyl-CoA Dehydrogenase Domain of Candida tropicalis Peroxisomal Multifunctional Enzyme Type 2===
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==See Also==
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*[[Alcohol dehydrogenase 3D structures|Alcohol dehydrogenase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_16574148}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 16574148 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16574148}}
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==About this Structure==
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2ET6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Candida_tropicalis Candida tropicalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ET6 OCA].
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==Reference==
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Crystal structure of yeast peroxisomal multifunctional enzyme: structural basis for substrate specificity of (3R)-hydroxyacyl-CoA dehydrogenase units., Ylianttila MS, Pursiainen NV, Haapalainen AM, Juffer AH, Poirier Y, Hiltunen JK, Glumoff T, J Mol Biol. 2006 May 19;358(5):1286-95. Epub 2006 Mar 30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16574148 16574148]
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[[Category: Candida tropicalis]]
[[Category: Candida tropicalis]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Glumoff, T.]]
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[[Category: Glumoff T]]
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[[Category: Hiltunen, J K.]]
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[[Category: Hiltunen JK]]
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[[Category: Ylianttila, M S.]]
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[[Category: Ylianttila MS]]
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[[Category: Beta-oxidation]]
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[[Category: Dehydrogenase]]
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[[Category: Mfe-2]]
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[[Category: Oxidoreductase]]
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[[Category: Peroxisome]]
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[[Category: Sdr]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 10:13:06 2008''
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Current revision

(3R)-Hydroxyacyl-CoA Dehydrogenase Domain of Candida tropicalis Peroxisomal Multifunctional Enzyme Type 2

PDB ID 2et6

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