2p7a

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:08, 21 February 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2p7a.png|left|200px]]
 
-
<!--
+
==Crystal Structure of Estrogen Related Receptor g in complex with 3-methyl phenol==
-
The line below this paragraph, containing "STRUCTURE_2p7a", creates the "Structure Box" on the page.
+
<StructureSection load='2p7a' size='340' side='right'caption='[[2p7a]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2p7a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P7A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P7A FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=43M:4-CHLORO-3-METHYLPHENOL'>43M</scene></td></tr>
-
{{STRUCTURE_2p7a| PDB=2p7a | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p7a OCA], [https://pdbe.org/2p7a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p7a RCSB], [https://www.ebi.ac.uk/pdbsum/2p7a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p7a ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/ERR3_HUMAN ERR3_HUMAN] Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity).<ref>PMID:19067653</ref> <ref>PMID:18063693</ref> <ref>PMID:11864604</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p7/2p7a_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p7a ConSurf].
 +
<div style="clear:both"></div>
-
===Crystal Structure of Estrogen Related Receptor g in complex with 3-methyl phenol===
+
==See Also==
-
 
+
*[[Estrogen-related receptor 3D structures|Estrogen-related receptor 3D structures]]
-
 
+
== References ==
-
<!--
+
<references/>
-
The line below this paragraph, {{ABSTRACT_PUBMED_17964775}}, adds the Publication Abstract to the page
+
__TOC__
-
(as it appears on PubMed at http://www.pubmed.gov), where 17964775 is the PubMed ID number.
+
</StructureSection>
-
-->
+
-
{{ABSTRACT_PUBMED_17964775}}
+
-
 
+
-
==About this Structure==
+
-
2P7A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P7A OCA].
+
-
 
+
-
==Reference==
+
-
Structural determination of estrogen-related receptor gamma in the presence of phenol derivative compounds., Abad MC, Askari H, O'Neill J, Klinger AL, Milligan C, Lewandowski F, Springer B, Spurlino J, Rentzeperis D, J Steroid Biochem Mol Biol. 2008 Jan;108(1-2):44-54. Epub 2007 Sep 14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17964775 17964775]
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Abad, M C.]]
+
[[Category: Abad MC]]
-
[[Category: Hormone receptor]]
+
-
[[Category: Three layered alpha helical sandwich]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 11:24:03 2008''
+

Current revision

Crystal Structure of Estrogen Related Receptor g in complex with 3-methyl phenol

PDB ID 2p7a

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2p7a"
Personal tools