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2qsg

From Proteopedia

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{{Seed}}
 
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[[Image:2qsg.png|left|200px]]
 
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<!--
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==Crystal structure of Rad4-Rad23 bound to a UV-damaged DNA==
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The line below this paragraph, containing "STRUCTURE_2qsg", creates the "Structure Box" on the page.
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<StructureSection load='2qsg' size='340' side='right'caption='[[2qsg]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2qsg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QSG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QSG FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=N:ANY+5-MONOPHOSPHATE+NUCLEOTIDE'>N</scene></td></tr>
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{{STRUCTURE_2qsg| PDB=2qsg | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qsg OCA], [https://pdbe.org/2qsg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qsg RCSB], [https://www.ebi.ac.uk/pdbsum/2qsg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qsg ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RAD4_YEAST RAD4_YEAST] Involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qs/2qsg_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qsg ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of Rad4-Rad23 bound to a UV-damaged DNA===
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==See Also==
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*[[DNA repair protein Rad4|DNA repair protein Rad4]]
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*[[UV excision repair protein|UV excision repair protein]]
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<!--
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__TOC__
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The line below this paragraph, {{ABSTRACT_PUBMED_17882165}}, adds the Publication Abstract to the page
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 17882165 is the PubMed ID number.
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[[Category: Large Structures]]
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-->
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{{ABSTRACT_PUBMED_17882165}}
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==About this Structure==
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2QSG is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QSG OCA].
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==Reference==
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Recognition of DNA damage by the Rad4 nucleotide excision repair protein., Min JH, Pavletich NP, Nature. 2007 Oct 4;449(7162):570-5. Epub 2007 Sep 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17882165 17882165]
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[[Category: Protein complex]]
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[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Min, J H.]]
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[[Category: Min J-H]]
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[[Category: Pavletich, N P.]]
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[[Category: Pavletich NP]]
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[[Category: Alpha-beta structure]]
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[[Category: Beta hairpin]]
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[[Category: Cyclobutanepyrimidine cpd dimer]]
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[[Category: Dna binding]]
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[[Category: Dna binding protein]]
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[[Category: Dna binding protein/dna complex]]
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[[Category: Dna repair]]
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[[Category: Dna-damage recognition]]
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[[Category: Mismatch dna]]
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[[Category: Nucleotide excision repair]]
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[[Category: Protein/dna complex]]
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[[Category: Transglutaminase fold]]
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[[Category: Ultraviolet uv damage]]
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[[Category: Xeroderma pigmentosum]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 11:59:31 2008''
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Current revision

Crystal structure of Rad4-Rad23 bound to a UV-damaged DNA

PDB ID 2qsg

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