303d

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{{Seed}}
 
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[[Image:303d.png|left|200px]]
 
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==META-HYDROXY ANALOGUE OF HOECHST 33258 ('HYDROXYL OUT' CONFORMATION) BOUND TO D(CGCGAATTCGCG)2==
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The line below this paragraph, containing "STRUCTURE_303d", creates the "Structure Box" on the page.
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<StructureSection load='303d' size='340' side='right'caption='[[303d]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[303d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=303D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=303D FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RO2:3-[5-[5-(4-METHYL-PIPERAZIN-1-YL)-1H-IMIDAZO[4,5-B]PYRIDIN-2-YL]-BENZIMIDAZOL-2-YL]-PHENOL'>RO2</scene></td></tr>
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{{STRUCTURE_303d| PDB=303d | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=303d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=303d OCA], [https://pdbe.org/303d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=303d RCSB], [https://www.ebi.ac.uk/pdbsum/303d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=303d ProSAT]</span></td></tr>
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</table>
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===META-HYDROXY ANALOGUE OF HOECHST 33258 ('HYDROXYL OUT' CONFORMATION) BOUND TO D(CGCGAATTCGCG)2===
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Clark GR]]
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[[Category: Gray EJ]]
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(as it appears on PubMed at http://www.pubmed.gov), where 9017011 is the PubMed ID number.
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[[Category: Leupin W]]
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[[Category: Neidle S]]
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{{ABSTRACT_PUBMED_9017011}}
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[[Category: Squire CJ]]
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==About this Structure==
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=303D OCA].
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==Reference==
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Designer DNA-binding drugs: the crystal structure of a meta-hydroxy analogue of Hoechst 33258 bound to d(CGCGAATTCGCG)2., Clark GR, Squire CJ, Gray EJ, Leupin W, Neidle S, Nucleic Acids Res. 1996 Dec 15;24(24):4882-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9017011 9017011]
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[[Category: Clark, G R.]]
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[[Category: Gray, E J.]]
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[[Category: Leupin, W.]]
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[[Category: Neidle, S.]]
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[[Category: Squire, C J.]]
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[[Category: B-dna]]
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[[Category: Complexed with drug]]
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[[Category: Double helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 12:05:19 2008''
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Current revision

META-HYDROXY ANALOGUE OF HOECHST 33258 ('HYDROXYL OUT' CONFORMATION) BOUND TO D(CGCGAATTCGCG)2

PDB ID 303d

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