1qsm

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{{Seed}}
 
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[[Image:1qsm.png|left|200px]]
 
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==Histone Acetyltransferase HPA2 from Saccharomyces Cerevisiae in Complex with Acetyl Coenzyme A==
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The line below this paragraph, containing "STRUCTURE_1qsm", creates the "Structure Box" on the page.
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<StructureSection load='1qsm' size='340' side='right'caption='[[1qsm]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1qsm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QSM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QSM FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene></td></tr>
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{{STRUCTURE_1qsm| PDB=1qsm | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qsm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qsm OCA], [https://pdbe.org/1qsm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qsm RCSB], [https://www.ebi.ac.uk/pdbsum/1qsm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qsm ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HPA2_YEAST HPA2_YEAST] In vitro, acetylates histone H3 'Lys-4' and 'Lys-14' and histone H4 'Lys-5' and 'Lys-12'.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qs/1qsm_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qsm ConSurf].
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<div style="clear:both"></div>
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===HISTONE ACETYLTRANSFERASE HPA2 FROM SACCHAROMYCES CEREVISIAE IN COMPLEX WITH ACETYL COENZYME A===
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==See Also==
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*[[Histone acetyltransferase 3D structures|Histone acetyltransferase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_10600387}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 10600387 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10600387}}
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==About this Structure==
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1QSM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QSM OCA].
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==Reference==
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Crystal structure of the histone acetyltransferase Hpa2: A tetrameric member of the Gcn5-related N-acetyltransferase superfamily., Angus-Hill ML, Dutnall RN, Tafrov ST, Sternglanz R, Ramakrishnan V, J Mol Biol. 1999 Dec 17;294(5):1311-25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10600387 10600387]
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[[Category: Histone acetyltransferase]]
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[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Single protein]]
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[[Category: Angus-Hill ML]]
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[[Category: Angus-Hill, M L.]]
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[[Category: Dutnall RN]]
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[[Category: Dutnall, R N.]]
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[[Category: Ramakrishnan V]]
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[[Category: Ramakrishnan, V.]]
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[[Category: Sternglanz R]]
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[[Category: Sternglanz, R.]]
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[[Category: Tafrov ST]]
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[[Category: Tafrov, S T.]]
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[[Category: Acetyltransferase]]
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[[Category: Protein-acetyl coenzyme a complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 12:06:16 2008''
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Current revision

Histone Acetyltransferase HPA2 from Saccharomyces Cerevisiae in Complex with Acetyl Coenzyme A

PDB ID 1qsm

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