This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1u5u

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:44, 14 February 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1u5u.png|left|200px]]
 
-
<!--
+
==The structure of an Allene Oxide Synthase reveals a novel use for a catalase fold==
-
The line below this paragraph, containing "STRUCTURE_1u5u", creates the "Structure Box" on the page.
+
<StructureSection load='1u5u' size='340' side='right'caption='[[1u5u]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1u5u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plexaura_homomalla Plexaura homomalla]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U5U FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-
{{STRUCTURE_1u5u| PDB=1u5u | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u5u OCA], [https://pdbe.org/1u5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u5u RCSB], [https://www.ebi.ac.uk/pdbsum/1u5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u5u ProSAT]</span></td></tr>
-
 
+
</table>
-
===The structure of an Allene Oxide Synthase reveals a novel use for a catalase fold===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/AOSL_PLEHO AOSL_PLEHO] Bifunctional enzyme which is responsible for allene oxide biosynthesis via a two-step reaction which involves conversion of arachidonic acid to a 8R-hydroperoxide intermediate followed by conversion of the hydroperoxide to allene oxide.<ref>PMID:9302294</ref> <ref>PMID:10559269</ref>
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_15625113}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 15625113 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u5/1u5u_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_15625113}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
1U5U is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Plexaura_homomalla Plexaura homomalla]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U5U OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u5u ConSurf].
-
 
+
<div style="clear:both"></div>
-
==Reference==
+
== References ==
-
The structure of coral allene oxide synthase reveals a catalase adapted for metabolism of a fatty acid hydroperoxide., Oldham ML, Brash AR, Newcomer ME, Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):297-302. Epub 2004 Dec 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15625113 15625113]
+
<references/>
-
[[Category: Hydroperoxide dehydratase]]
+
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Plexaura homomalla]]
[[Category: Plexaura homomalla]]
-
[[Category: Single protein]]
+
[[Category: Brash AR]]
-
[[Category: Brash, A R.]]
+
[[Category: Newcomer ME]]
-
[[Category: Newcomer, M E.]]
+
[[Category: Oldham ML]]
-
[[Category: Oldham, M L.]]
+
-
[[Category: Allene oxide synthase]]
+
-
[[Category: Catalase]]
+
-
[[Category: Eicosanoid]]
+
-
[[Category: Fusion protein]]
+
-
[[Category: Heme]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 12:12:38 2008''
+

Current revision

The structure of an Allene Oxide Synthase reveals a novel use for a catalase fold

PDB ID 1u5u

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools