2ukd

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{{Seed}}
 
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[[Image:2ukd.png|left|200px]]
 
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==UMP/CMP KINASE FROM SLIME MOLD COMPLEXED WITH ADP, CMP==
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The line below this paragraph, containing "STRUCTURE_2ukd", creates the "Structure Box" on the page.
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<StructureSection load='2ukd' size='340' side='right'caption='[[2ukd]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2ukd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UKD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UKD FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=C5P:CYTIDINE-5-MONOPHOSPHATE'>C5P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_2ukd| PDB=2ukd | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ukd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ukd OCA], [https://pdbe.org/2ukd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ukd RCSB], [https://www.ebi.ac.uk/pdbsum/2ukd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ukd ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KCY_DICDI KCY_DICDI] This UMP-CMP kinase uses preferentially ATP as phosphate donor and is specific for UMP and CMP.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uk/2ukd_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ukd ConSurf].
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<div style="clear:both"></div>
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===UMP/CMP KINASE FROM SLIME MOLD COMPLEXED WITH ADP, CMP===
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==See Also==
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*[[UMP/CMP kinase|UMP/CMP kinase]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_9280438}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 9280438 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9280438}}
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==About this Structure==
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2UKD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UKD OCA].
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==Reference==
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Structures of active conformations of UMP kinase from Dictyostelium discoideum suggest phosphoryl transfer is associative., Schlichting I, Reinstein J, Biochemistry. 1997 Aug 5;36(31):9290-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9280438 9280438]
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[[Category: Cytidylate kinase]]
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[[Category: Dictyostelium discoideum]]
[[Category: Dictyostelium discoideum]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Reinstein, J.]]
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[[Category: Reinstein J]]
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[[Category: Schlichting, I.]]
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[[Category: Schlichting I]]
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[[Category: Nmp kinase]]
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[[Category: Nucleoside monophosphate kinase]]
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[[Category: Phosphoryl transfer]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 12:58:29 2008''
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Current revision

UMP/CMP KINASE FROM SLIME MOLD COMPLEXED WITH ADP, CMP

PDB ID 2ukd

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